Protein Alignment Mmp1 and Mmp12

DIOPT Version :9

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_446415.2
• Gene: Mmp12 / 117033
• RGDID: 620195
• Length: 477
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 183/510 - (35%)
• Similarity: 252/510 - (49%)
• Gaps: 75/510 - (14%)

  Fly    10 IVVGTLFSI-MAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAG 73
            :|:..|.|: ::|..:||::.:..||.|||:| :.....|.|.:....::......::|.|.|.|
  Rat    17 LVLVLLVSLQVSACGAAPMNESEFAEWYLSRF-FDYQGDRIPMTKTKTNRNLLEEKLQEMQQFFG 80

  Fly    74 LNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVD 138
            |.:||:||..|:|:|...||||      .|.:..|...|.|||..:.|||:|..|...:||.|||
  Rat    81 LEVTGQLDTSTLKIMHTSRCGV------PDVQHLRAVPQRSRWMKRYLTYRIYNYTPDMKRADVD 139

  Fly   139 AEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFG--GDAH 201
            ....:||.|||:.|.|.|.:...|...|.|.|...:|||...|||:||||||||:|..|  ||||
  Rat   140 YIFQKAFQVWSDVTPLRFRKIHKGEADITILFAFGDHGDFYDFDGKGGTLAHAFYPGPGIQGDAH 204

  Fly   202 FDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEP-VFKLDEDDKAAIQS 265
            ||:||.|| .|.:|||||.||.||.||||||.||:...::|.|.||...| .|:|..||..:|||
  Rat   205 FDEAETWT-KSFQGTNLFLVAVHELGHSLGLPHSNNPKSIMYPTYRYLHPNTFRLSADDIHSIQS 268

  Fly   266 LYGRKTNQLRPTNVYPATTQRPYSPPKVPLDDSICKDSKVDTLFNSAQGETYAFKGDK------- 323
            |||........||        |.|||......|:..|: |.|:            |||
  Rat   269 LYGAPVKNPSLTN--------PGSPPSTVCHQSLSFDA-VTTV------------GDKIFFFKDW 312

  Fly   324 --YYKLTTDSVEEGYPQL----ISKGWPGLPGNIDAAFTYKNG---KTYFFKGTQYWRYQGRQMD 379
              :::|      .|.|..    ||..||.:|..|.||  |:.|   :.:.||..:||.......:
  Rat   313 FFWWRL------PGSPATNITSISSMWPTIPSGIQAA--YEIGGRNQLFLFKDEKYWLINNLVPE 369

  Fly   380 GVYPKEI-SEGFTGIPDHLDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPIS-NWEGV 442
            ..||:.| |.||......:|||:......|:|||...::||:| .::..:.|:|||.|| ::.|:
  Rat   370 PHYPRSIHSLGFPASVKKIDAAVFDPLRQKVYFFVDKQYWRYD-VRQELMDAAYPKLISTHFPGI 433

  Fly   443 PNNLDAALKYTNGYTYFFKGDKYYRF----HDARFAVDSATPPFPRPTAHWWFGC 493
            ...:||.|.:...| |.|:|.....:    |.....:.|.:          ||||
  Rat   434 RPKIDAVLYFKRHY-YIFQGAYQLEYDPLLHRVTKTLSSTS----------WFGC 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773	19/55 (35%)
		Peptidase_M10	115..268	CDD:278824	81/155 (52%)
		ZnMc_MMP	115..268	CDD:239805	81/155 (52%)
		HX	298..493	CDD:238046	58/216 (27%)
Mmp12	NP_446415.2	PG_binding_1	41..95	CDD:279773	19/54 (35%)
		Peptidase_M10	116..271	CDD:278824	81/155 (52%)
		ZnMc_MMP	116..271	CDD:239805	81/155 (52%)
		HX	293..477	CDD:238046	58/216 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342130
Domainoid	1	1.000	151	1.000	Domainoid score	I4255
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	1	1.000	-	-		FOG0000127
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850