DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mmp1 and mmp23ba

DIOPT Version :9

Sequence 1:	NP_726473.2	Gene:	Mmp1 / 37949	FlyBaseID:	FBgn0035049	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	XP_009302611.1	Gene:	mmp23ba / 101882601	ZFINID:	ZDB-GENE-030131-9548	Length:	371	Species:	Danio rerio

Alignment Length:	294	Identity:	88/294 - (29%)
Similarity:	122/294 - (41%)	Gaps:	73/294 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 SRSKRYAL--QGSRWRVKNLTYKISKYPKR-LKRVDVDAEIGRAFAVWSEDTDLTFTRKTSG-PV 164
            ||:|||.|  :..:|....:|||:..:|:. |...|....|.:||::||:.:..:|....|. ..
Zfish    55 SRNKRYTLTPEKLKWDNFKMTYKLLSFPRNLLNATDTRRGISKAFSMWSDVSPFSFREVPSDQEA 119

  Fly   165 HIEIKFVESEHGD------GDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRG-------- 215
            .|:|.|....|.|      ...|||..|.|||||||. .|:.||||.|.|.:|:.|.
Zfish   120 DIKIGFYSVNHTDCLHSHLHHCFDGITGELAHAFFPQ-TGEIHFDDDEYWILGNMRFSWNKGVWL 183

  Fly   216 TNLFQVAAHEFGHSLGLSHSDQSSALM--APFYRGFEPVFKLDEDDKAAIQSLYG---------- 268
            |:|..|||||.||.|||.||....|||  .....|.:   .:.:|:...:..|||
Zfish   184 TDLVHVAAHEIGHVLGLMHSQNPKALMHLNATLTGRK---LITQDEVWGLHRLYGCLDRFFICPS 245

  Fly   269 ----------RKTNQLR-PTNV-----YPATTQRP-YSPPKVPLDDSICKDSKVDTLFNSAQGET 316
                      ||..|.. |::.     :|..|.|| .:||:.       |...|      .:|:.
Zfish   246 WARKGYCDSKRKLMQKHCPSSCDFCYEFPFPTARPTTAPPRT-------KHKFV------VEGKN 297

  Fly   317 YAF---------KGDKYYKLTTDSVEEGYPQLIS 341
            ..|         ||..|:....:.:|..:|..||
Zfish   298 LTFRCGKKIAAKKGKIYWYKDGELLEFSHPGYIS 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773
		Peptidase_M10	115..268	CDD:278824	59/170 (35%)
		ZnMc_MMP	115..268	CDD:239805	59/170 (35%)
		HX	298..493	CDD:238046	11/53 (21%)
mmp23ba	XP_009302611.1	Peptidase_M10	68..235	CDD:278824	59/170 (35%)
		ZnMc_MMP	68..235	CDD:239805	59/170 (35%)
		ShKT	236..270	CDD:214586	4/33 (12%)
		IG_like	292..369	CDD:214653	10/46 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920