Protein Alignment Mmp1 and mmp24

DIOPT Version :9

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_031750429.1
• Gene: mmp24 / 100492405
• XenbaseID: XB-GENE-1009940
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 605
• Identity: 214/605 - (35%)
• Similarity: 302/605 - (49%)
• Gaps: 98/605 - (16%)

  Fly    18 IMAAAQSAPVSTTTQAEIYLSQFGY-LPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELD 81
            :.|.:.::....|.....:|..:|| ||...|   .|.|...:...||:...|.|.|:.:|||||
 Frog    54 VFARSGTSITDGTPHVPRWLKTYGYLLPYDIR---ISALQSGKAMQSAVSAMQQFYGIPVTGELD 115

  Fly    82 AETMKLMSLPRCGVRDRVGTGD-SRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDAEIGRAF 145
            ..|::.|..|||||.|...... .|:|||||.|.:||.|::||.|..|..::..:|....|.:||
 Frog   116 QMTIEWMKKPRCGVPDHPHLSHRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAF 180

  Fly   146 AVWSEDTDLTF----------TRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFF--PVFGG 198
            .||.:.|.|||          .||.:   .|.|.|....|||...|||:||.||||:|  |..||
 Frog   181 DVWQKVTPLTFEEIPYSEIKNERKEA---DIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGG 242

  Fly   199 DAHFDDAELWTIGSPR--GTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEP-VFKLDEDDK 260
            |.|||..|.||:|:..  |.:||.||.||.||:|||.||:..||:|||||:..|. .|||.:||.
 Frog   243 DTHFDSDEPWTLGNSNHDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFYQYMETHNFKLPQDDL 307

  Fly   261 AAIQSLYGRKTNQLRPTNVYP--------ATTQRPYS----PPKVPLDD---------SICKDSK 304
            ..||.:||.....:.||...|        :|::|.:.    ||:.||.|         :||
 Frog   308 QGIQKIYGPPAETMEPTRPLPTLPPRRIHSTSERKHERQPRPPRPPLGDKPPSTGSRPNIC---- 368

  Fly   305 VDTLFNSA---QGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAAFTYKNGKTYFFK 366
             |..||:.   :||.:.||...:::|..:.|:||||..|.:.|.|||..||||:...:||..|||
 Frog   369 -DGNFNTVALFRGEMFVFKDRWFWRLRNNKVQEGYPMQIEQFWKGLPPKIDAAYERSDGKFVFFK 432

  Fly   367 GTQYWRYQGRQMDGVYPKEISEGFTGIP-DHLDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKA 430
            |.:||.::....:..||..:.|..:.:| :.:|.|:.|....|.|||||.::||::..|| ....
 Frog   433 GDKYWVFKEVTAEPGYPHSLVELGSCLPREGIDTALRWETFSKTYFFKGDRYWRYNEEKR-AADP 496

  Fly   431 SYPKPISNWEGVPNNLDAALKYTNG-YTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGCK 494
            .|||||:.|:|:|.:...|.....| ||||:||.:|::|.:.|..|:   |.:||.....|.||.
 Frog   497 GYPKPITIWKGIPESPQGAFVSKEGSYTYFYKGREYWKFDNQRLTVE---PGYPRSIVKDWMGCN 558

  Fly   495 NTPSSTGNIVEGSDNEFEQHSMIPHADDGNGDDFDAAVGDHQSNDEPIVPEVAERTGNGAMSQSK 559
            .         :..||..::  .:||      ||.|..|   ..||.|
 Frog   559 Q---------KEVDNSKDR--QLPH------DDVDIMV---TINDVP------------------ 585

  Fly   560 LTSSSAVSTVITTIL-MCLV 578
             ::.:|::.||..|| :|::
 Frog   586 -STVNAIAVVIPCILSLCIL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:279773	19/56 (34%)
		Peptidase_M10	115..268	CDD:278824	75/167 (45%)
		ZnMc_MMP	115..268	CDD:239805	75/167 (45%)
		HX	298..493	CDD:238046	73/199 (37%)
mmp24	XP_031750429.1	PG_binding_1	71..122	CDD:396175	19/53 (36%)
		Peptidase_M10	150..315	CDD:395334	75/167 (45%)
		HX	365..557	CDD:238046	73/200 (37%)
		DUF3377	563..633	CDD:403153	17/72 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I12189
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2436
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47536
Panther	1	1.100	-	-	O	PTHR10201
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.160