Protein Alignment Mmp1 and mmp25b

DIOPT Version :10

• Sequence 1: NP_726473.2
• Gene: Mmp1 / 37949
• FlyBaseID: FBgn0035049
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_002663942.1
• Gene: mmp25b / 100333601
• ZFINID: ZDB-GENE-100308-4
• Length: 573
• Species: Danio rerio
• Alignment Length: 529
• Identity: 197/529 - (37%)
• Similarity: 271/529 - (51%)
• Gaps: 55/529 - (10%)

  Fly     4 CQSSVFIVVGTLFSIMAAAQSAPVSTTTQAEI-YLSQFGYLPASARNPASSGLHDQRTWVSAIEE 67
            |...||         .:|..||||.......: :||::||||  ..:|.:..|..:.....||.|
Zfish    14 CPMLVF---------FSAVHSAPVKDQYSRGVDWLSRYGYLP--PLDPRTGQLQSKDGIERAIRE 67

  Fly    68 FQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDS----RSKRYALQGSRWRVKNLTYKISKY 128
            .|.||||..||:||::|:.||:.|||.:.|.:|..|.    |.||||..|.||...::|:.:..|
Zfish    68 MQRFAGLKETGKLDSDTLTLMNTPRCSLPDIIGIEDKLKKRRRKRYATTGLRWTKSDITWSVQNY 132

  Fly   129 P---KRLKRVDVDAEIGRAFAVWSEDTDLTFTRKTSGP---VHIEIKFVESEHGDGDAFDGQGGT 187
            |   |||....||..|..|...||:.|:|.|...:|..   ..|.|.|..|.|.||..|||:|||
Zfish   133 PSVHKRLTPTQVDPIISYALKAWSDVTNLNFYGASSSEKDRADIRISFARSLHDDGYPFDGKGGT 197

  Fly   188 LAHAFFP---VFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGF 249
            |||||||   ...||.||||.|:||.....||:||.||.|||||:||||||..|.::|.|:|:|.
Zfish   198 LAHAFFPGESDVAGDTHFDDDEIWTYLDESGTDLFAVAVHEFGHALGLSHSSSSPSIMKPYYQGS 262

  Fly   250 ---EPVFKLDEDDKAAIQSLYGRKTNQLRPTNVYPATTQRPYSP---PKVPL--DDSI---CKDS 303
               ...:.|.:||:.|||||||||.:...|:...| |:..|..|   ||.|:  |.||   | :.
Zfish   263 VGDVGSYILPDDDREAIQSLYGRKISSPTPSPNKP-TSHLPKPPATYPKGPVKPDPSIQNRC-EG 325

  Fly   304 KVDTLFNSAQGETYAFKGDKYYKL-TTDSVEEGYPQLISKGWPGLP---GNIDAAFTYK-NGKTY 363
            ..|.:.| .:||.:.|||..:::: .|.|:....|..|...|.|||   ..:||.:..| :....
Zfish   326 GFDAVAN-LRGEVFFFKGPYFWRIQRTGSLVSFQPAHIKNFWMGLPPTTNKVDAVYERKVDNAII 389

  Fly   364 FFKGTQYWRYQGRQMDGVYPKEISEGFTGIPD-----HLDAAMVWGGNGKIYFFKGSKFWRFDPA 423
            ||.|:|||.::..::...||:.:|:......|     .:|||.:|..|||.|.|.|.:||||...
Zfish   390 FFIGSQYWVFKNTEVLPGYPRPLSDWGMITQDGRKVMRVDAAFIWAHNGKTYIFSGGEFWRFSEG 454

  Fly   424 KRPPVK---ASYPKPISNWEGVPNNLDAALKYTNGYTYFFKGDKYYRFHDARFAVDSATPPFPRP 485
            :...::   ..||:..:.|:|.|:|.|..:.:..|..||||.:.|:...:......|.|   .:.
Zfish   455 RETELRGPDTGYPRNTNLWKGAPSNPDDVITWGQGDAYFFKDNSYWVLKNGEMDQTSVT---KKS 516

  Fly   486 TAHWWFGCK 494
            ||..|..|:
Zfish   517 TAVDWMMCQ 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp1	NP_726473.2	PG_binding_1	32..88	CDD:460223	21/56 (38%)
		Peptidase_M10	115..268	CDD:425668	77/164 (47%)
		HX	298..493	CDD:238046	63/210 (30%)
mmp25b	XP_002663942.1	PG_binding_1	38..88	CDD:460223	21/51 (41%)
		ZnMc_MMP	119..284	CDD:239805	77/164 (47%)
		HX	321..524	CDD:238046	61/207 (29%)