DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4806 and WHI3

DIOPT Version :9

Sequence 1:	NP_611955.2	Gene:	CG4806 / 37948	FlyBaseID:	FBgn0260456	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_014202.1	Gene:	WHI3 / 855524	SGDID:	S000005141	Length:	661	Species:	Saccharomyces cerevisiae

Alignment Length:	244	Identity:	48/244 - (19%)
Similarity:	89/244 - (36%)	Gaps:	53/244 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   346 ADGVSASDMAKRHELEQVKTQVLKNLNRFVSRNRLSIHNLPQNYD---NEKLKQMALTYTGFRPH 407
            |:||.:.::.|::....:.:..|::.|......|..:.||..||.   |.|.:....::
Yeast   125 AEGVKSIELQKKNSSSSITSASLEDENDIFIIARFELLNLAINYAVILNSKNELFGPSF------ 183

  Fly   408 ECRVMREHKVTPEHPQGKSKGFGFLSF-------DTHQRALAALRKLNN---NPNIFGTQSRPIV 462
                  .:|.|.|.....:|  ..:||       ||     :.|.|.|:   .|::...:||
Yeast   184 ------PNKTTVEIIDDTTK--NLVSFPSSAIFNDT-----SRLNKSNSGMKRPSLLSQRSR--- 232

  Fly   463 AFSIEDRAVHKIKEKRTERSKQNNPTYQNKQQERKERRQQKRNGQETKTPVPQADNKSKLQKHIK 527
             ||..|...:.....:.:..:|.....|.:|...::...|:.|.|:..:.:|.:.....:..|
Yeast   233 -FSFSDPFSNDSPLSQQQSQQQQQQPQQPQQHSTQKHSPQQCNQQQVNSSIPLSSQGQVIGLH-- 294

  Fly   528 KLEASRAAKAEGKVAEKKQLSDVQGDFVGTAAKPGTSLKMRSKKKIVEQ 576
                |..:..:..|....|.||:           |.|..:|...:|.|:
Yeast   295 ----SNHSHQDLSVESTIQTSDI-----------GKSFLLRDNTEINEK 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4806	NP_611955.2	RRM	<2..>154	CDD:223796
		RRM_SF	49..124	CDD:302621
		RRM3_RBM28_like	230..306	CDD:240861
		RRM4_RBM28_like	379..468	CDD:240862	23/101 (23%)
WHI3	NP_014202.1	RRM	450..>648	CDD:223796
WHI3	NP_014202.1	RRM_scw1_like	536..624	CDD:409691
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343560
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930