DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4806 and AT2G21440

DIOPT Version :9

Sequence 1:	NP_611955.2	Gene:	CG4806 / 37948	FlyBaseID:	FBgn0260456	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_565513.1	Gene:	AT2G21440 / 816683	AraportID:	AT2G21440	Length:	1003	Species:	Arabidopsis thaliana

Alignment Length:	746	Identity:	205/746 - (27%)
Similarity:	335/746 - (44%)	Gaps:	137/746 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLKDDAAESQSQPETGVRKRRNPFNTQRLKEEKERRQKKRARLIVRNISYKSTEDSLREHFGQWG 72
            |:|...|......:|.|  :.|....::|..|..:.||  .:||:||:.:::....::..|...|
plant   295 SVKSACAAVAKLHQTEV--KGNLIWARQLGGEGSKAQK--WKLIIRNLPFQAKPSDIKVVFSAVG 355

  Fly    73 TLEDVHILKRGD-GKLVGCAFVQYETINQATKAILNSNGKELLGRKVFVDWALGKDEY------- 129
            .:.||.|.|..: |...|.|||::.....|..||...||.....|.:.||||:.|:.|
plant   356 FVWDVFIPKNFETGLPKGFAFVKFTCKKDAANAIKKFNGHMFGKRPIAVDWAVPKNIYNGAADAT 420

  Fly   130 ---VSKNPKDEEPDEKKPKVEVKEEN---------GDEKEVKEESDAEVGKEDESSGEDSDAESG 182
               ...:.:..:.|.:...|:::|.:         ||:.:..|:..   .|..||...|.|..:.
plant   421 TASADGDKEGSDGDSENSSVDLEEVDEAVESHPPPGDDTDDDEDGS---NKLTESDALDKDVGTD 482

  Fly   183 ---EDEED------------------SGESEDEENDEDHKENKDELKSKLDIKNVK--------- 217
               |||.|                  :.|.|.||:|          ||||...:.|
plant   483 MNFEDEADVARKVLKNLLASSKGSTATPEGETEESD----------KSKLKSSSTKPVADSSGVS 537

  Fly   218 -------------REKQISNDVQEGCTVFIKNVPFDAEDADLRKACRKFGLVSYAIINRQAVSGH 269
                         :|.|.::|.:.  |:||:|:|||....::::....||.|....:....|:..
plant   538 EPLKSGKTKVVAPKETQDNDDFER--TLFIRNLPFDVTKEEVKQRFTVFGEVESLSLVLHKVTKR 600

  Fly   270 SKGTAFVKFKAKESADLCLQA-----GTEFKLMDEVLDPHPALSREEMKSKQSQENKKDDAK--D 327
            .:||||||||..:::...:.|     |....|....|:...|:.:   |:.:..|.||.:.|  |
plant   601 PEGTAFVKFKTADASVAAISAADTASGVGVLLKGRQLNVMRAVGK---KAAKDIELKKTEEKNVD 662

  Fly   328 SRNLYLAREGLIMAGAKAADGVSASDMAKRHELEQVKTQVLKNLNRFVSRNRLSIHNLPQNYDNE 392
            .||||||:||.|:....||:||||.||.||..|.:.|.::|::.|..|||.||.|:|||::.:.:
plant   663 HRNLYLAKEGQILDDTPAAEGVSAEDMDKRRRLHENKMKMLQSPNFHVSRTRLVIYNLPKSMNPK 727

  Fly   393 KLKQM---ALTYTGFRPHECRVMREHKVTPEHPQGK------SKGFGFLSFDTHQRALAALRKLN 448
            :|.::   |:|....:...|  :|:.|......:||      |:|..|:.|..|:.||.|||.||
plant   728 QLNRLLVDAVTSRATKQKPC--IRQIKFLQNEKKGKVDTKNYSRGVAFVEFTEHEHALVALRVLN 790

  Fly   449 NNPNIFGTQSRPIVAFSIEDRAVHKIKEKRTERSKQNNPTYQNKQQERKERRQ-----QKRNGQE 508
            |||..||.|.||::.|::::....||:|.:.::.:|.....::.||:.....|     .||..:|
plant   791 NNPETFGPQHRPVIEFAVDNVQKLKIREAKQQQFQQREKHNESDQQQANGEAQAPDNKYKRKTRE 855

  Fly   509 TKTPVPQADNKSKLQK---HIKKLEASRAAKAEGKVAEKKQLSDVQGDFVGTAAKPGTSLK--MR 568
            .....|:.:|.::.:|   ...|.||......:...||||:.       :.|..||.::.|  :.
plant   856 GDNTGPRKENAARFKKGPREESKEEAKSNIAVKDNAAEKKRP-------IRTQEKPSSNKKGQLM 913

  Fly   569 SKKKIVEQAKEHLKKVKTEKRKQKNKKIR--ESHLAERKANNRPKQGR----KKETDDLRPLINK 627
            .:|:..|:....:.|..:|.||:|..:.|  |:...:||   |.|||:    .:..|.|..||.|
plant   914 RQKETTEKPDPKISKDLSEPRKRKFGEDRGEENRNGQRK---RKKQGQGQGGAEVVDKLDLLIEK 975

  Fly   628 YKNMISGNQGGGG---VTGGKIKKPKRTKWY 655
            |::..|.:....|   .:.|:::     :|:
plant   976 YRSKFSQSSAKTGPQKQSSGQVR-----RWF 1001

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4806	NP_611955.2	RRM	<2..>154	CDD:223796	40/165 (24%)
		RRM_SF	49..124	CDD:302621	24/75 (32%)
		RRM3_RBM28_like	230..306	CDD:240861	23/80 (29%)
		RRM4_RBM28_like	379..468	CDD:240862	35/97 (36%)
AT2G21440	NP_565513.1	RRM1_RBM28_like	21..99	CDD:240859
		ELAV_HUD_SF	24..411	CDD:273741	35/119 (29%)
		RRM_SF	<291..>316	CDD:302621	6/22 (27%)
		RRM2_RBM28_like	332..408	CDD:240860	24/75 (32%)
		RRM3_RBM28_like	561..642	CDD:240861	23/82 (28%)
		RRM4_RBM28_like	713..810	CDD:240862	35/98 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0127
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	207	1.000	Inparanoid score	I1274
OMA	1	1.010	-	-		QHG55464
OrthoDB	1	1.010	-	-		D1181291at2759
OrthoFinder	1	1.000	-	-		FOG0003903
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102701
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2687
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.740