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Protein Alignment CG4806 and RBM28

DIOPT Version :9

Sequence 1:	NP_611955.2	Gene:	CG4806 / 37948	FlyBaseID:	FBgn0260456	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_060547.2	Gene:	RBM28 / 55131	HGNCID:	21863	Length:	759	Species:	Homo sapiens

Alignment Length:	720	Identity:	244/720 - (33%)
Similarity:	366/720 - (50%)	Gaps:	113/720 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KSLKDDAAESQSQPETGVRKRRNPFNTQRLKEEKERRQK---KRARLIVRNISYKSTEDSLREHF 68
            |.|::...|          |.:|..:....||.|.::.|   |:||||:||:|:|.:||.|:..|
Human    80 KKLRNKTKE----------KGKNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVF 134

  Fly    69 GQWGTLEDVHILKRGDGKLVGCAFVQYETINQATKAILNSNGKELLGRKVFVDWALGKDEY---- 129
            .|:|.:.:|:|.::.|||:.|..|||::.:.:|.||:...|.||:.||.|.||||:.||:|
Human   135 AQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIKGRTVAVDWAVAKDKYKDTQ 199

  Fly   130 --------VSKNPKDEEPDEKKPKVE---VKEENGDEKEVKEESDAEVGKEDES----------- 172
                    .|...|.:|..:||.:.|   .:|||.|:.:..:|.|.....|||.
Human   200 SVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKP 264

  Fly   173 -------------------SGEDSDAESGEDEEDSGESEDEENDEDHKENKDELKSKLDIKNVKR 218
                               |.||||.|..:..:|..|....:...:.:|:|     .:.:.| |:
Human   265 VQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEELAQSDTSTEEQEDK-----AVQVSN-KK 323

  Fly   219 EKQISNDVQEGCTVFIKNVPFDAEDADLRKACRKFGLVSYAIINRQAVSGHSKGTAFVKFKAKES 283
            ::::.:||.||.||||:|:.||:|:.:|.:..::||.:.|..|.....:.||||.||.:|..:|:
Human   324 KRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEA 388

  Fly   284 ADLCLQAGTE------FKLMDEVLDPHPALSREEMKSKQSQENKKDDAKDSRNLYLAREGLIMAG 342
            |..||.|.:.      .||....|....|::|:|....|:.:.||...  :|||||||||||.||
Human   389 AQKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAKLQTTKVKKPTG--TRNLYLAREGLIRAG 451

  Fly   343 AKAADGVSASDMAKRHELEQVKTQVLKNLNRFVSRNRLSIHNLPQNYDNEKLKQMALTYT----G 403
            .|||:||||:|||||...|.:|.|.||:.|.||||.||.:||||:..|:::|:::.|:.|    |
Human   452 TKAAEGVSAADMAKRERFELLKHQKLKDQNIFVSRTRLCLHNLPKAVDDKQLRKLLLSATSGEKG 516

  Fly   404 FRPHECRVMREHKVTPEHPQGKSKGFGFLSFDTHQRALAALRKLNNNPNIFGTQSRPIVAFSIED 468
            .|..||||||:.|....:.:|:|.|:.|..|..|:.||.|||.:||||.|||...||||.||:||
Human   517 VRIKECRVMRDLKGVHGNMKGQSLGYAFAEFQEHEHALKALRLINNNPEIFGPLKRPIVEFSLED 581

  Fly   469 RAVHKIKEKRTERSKQ---NNPTY---QNKQQERKERRQQKRNGQETKTPVPQADNKSKLQKHIK 527
            |...|:||.|.:||.|   :.|..   |..|.|..:.:|||.....|       :.:||:....|
Human   582 RRKLKMKELRIQRSLQKMRSKPATGEPQKGQPEPAKDQQQKAAQHHT-------EEQSKVPPEQK 639

  Fly   528 KLEASRA-----AKAEGKVAEKKQLSD--VQGDFVGTAAKPGTSLKMRSKKKIVEQAKEHLKKVK 585
            :...|.:     .|||   .|:.:|.|  .:...:...:..|..:::|.|.|:   ...|.||.|
Human   640 RKAGSTSWTGFQTKAE---VEQVELPDGKKRRKVLALPSHRGPKIRLRDKGKV---KPVHPKKPK 698

  Fly   586 TEKRKQKNKKIRESHLAERKANNRPKQGRKKETDDLRPLINKYKNMISGNQGGGGVTGGKIKKPK 650
            .:..:.|.:|   ..|:..:.:.:..:|.|.|| ....|:.:||..:.|...|..:.       |
Human   699 PQINQWKQEK---QQLSSEQVSRKKAKGNKTET-RFNQLVEQYKQKLLGPSKGAPLA-------K 752

  Fly   651 RTKWY 655
            |:||:
Human   753 RSKWF 757

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.