Protein Alignment CG4806 and rbm-28

DIOPT Version :9

• Sequence 1: NP_611955.2
• Gene: CG4806 / 37948
• FlyBaseID: FBgn0260456
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_497077.2
• Gene: rbm-28 / 175145
• WormBaseID: WBGene00011043
• Length: 608
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 192/586 - (32%)
• Similarity: 291/586 - (49%)
• Gaps: 97/586 - (16%)

  Fly     7 KSLKDDAAESQSQPETGVRKRRNPFNTQRLKEEKERRQKKRARLIVRNISYKSTEDSLREHFGQW 71
            |..:.:|.|.:   ::.:|||   |...:|||         .|||:||:.:|:.::.|:......
 Worm    69 KRARPEATEGE---KSAIRKR---FEQAKLKE---------WRLIIRNLPFKTKKEDLQNLCSNI 118

  Fly    72 GTLEDVHIL--KRGDGK-LVGCAFVQYETINQATKAILNSNGKELLGRKVFVDWALGKDEY---- 129
            |...:: :|  .|.|.| ..|..|:|:.....|.|.....|..::|||.|..||||.||.|
 Worm   119 GKFVEI-VLPPSRKDPKTCAGFGFIQFVEKADAEKGREFFNTNKVLGRSVAADWALDKDTYETNA 182

  Fly   130 ---------VSKNPKDEEPDEKKPKVEVKEENGDEKEVKEESDAEVGKEDESSGEDSDAESGEDE 185
                     |.|..|||:|:||..|.       ||:|.:|||:   |.||.|          |..
 Worm   183 HEEKQHLKKVVKVEKDEKPEEKSKKF-------DEEEGEEESE---GSEDGS----------EAF 227

  Fly   186 EDSGESEDEENDEDHKENKDELKSKLDIKNVKREKQISNDVQEGCTVFIKNVPFDAEDADLRKAC 250
            |.|..|||:|:||:..:..         ||.|.:.:....:.||..||::|:.:|.::..:::..
 Worm   228 EASEASEDDEDDEEPAKKP---------KNPKAQLKTDESITEGKVVFLRNLSYDTKEELIKEEL 283

  Fly   251 RKFGLVSYAIINRQAVSGHSKGTAFVKFKAKESADLCLQAGTEFKLMD-EVLDPHPALSREEMKS 314
            .|||.:..|||.:...||||||||||.|.....|..|::...:..::| .::..:.|:.|:|...
 Worm   284 SKFGKIDLAIICKYKDSGHSKGTAFVHFSTPIEASNCIEGVEDGVIIDNRLVKANLAIPRKEAAD 348

  Fly   315 KQSQENKKDDAKDSRNLYLAREGLIMAGAKAADGVSASDMAKRHELEQVKTQVLKNLNRFVSRNR 379
            .:.::..| ..||.|||.|||.|||..|..||.|:|..|.|||..:.:...:.|:|.|.|:|..|
 Worm   349 MEKEKLTK-VPKDKRNLRLARFGLIRDGTAAAAGMSKDDAAKRERIAEAMRKKLENTNMFISPVR 412

  Fly   380 LSIHNLPQNYDNEKLKQMALTYT--GFRPHECRV-MREHKVTPEHPQGKSKGFGFLSFDTHQRAL 441
            |.||||||..::.|||::|..:|  |....|||| |.:.::||: .:.||.||||::|..|..||
 Worm   413 LCIHNLPQKINDVKLKELAQKFTSPGALITECRVWMDKKRLTPD-GKPKSSGFGFVAFKEHMHAL 476

  Fly   442 AALRKLNNNPNIFGTQSRPIVAFSIEDRAVHKIKEKRTERSKQNNPTYQNKQQER----KERRQQ 502
            ..|:|||||...|....||||.||:|:....:.:.:|..:    |.|  .|..||    |.|:|.
 Worm   477 ECLKKLNNNAETFHKDHRPIVEFSVENLLALQARARRNVK----NTT--EKMSERVVNEKIRQQV 535

  Fly   503 KRNGQETKTP----VPQADNK--------SKLQKHIKKLEASRAAK--------AEGKVAEKKQL 547
            |::..|..|.    :|:...|        .:.:|::.:::|::.:|        .:.|.|.||.:
 Worm   536 KQSIGEVHTAGMKFLPKFTGKKIRHRNLSGRAKKNVDRVKAAKNSKQPEMPTSVGKKKKAMKKNV 600

  Fly   548 S 548
            |
 Worm   601 S 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4806	NP_611955.2	RRM	<2..>154	CDD:223796	48/162 (30%)
		RRM_SF	49..124	CDD:302621	24/77 (31%)
		RRM3_RBM28_like	230..306	CDD:240861	24/76 (32%)
		RRM4_RBM28_like	379..468	CDD:240862	44/91 (48%)
rbm-28	NP_497077.2	RRM	36..>172	CDD:223796	33/118 (28%)
		RRM2_RBM28_like	96..173	CDD:240860	24/77 (31%)
		RRM3_RBM28_like	263..340	CDD:240861	24/76 (32%)
		RRM4_RBM28_like	411..503	CDD:240862	44/92 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I7080
eggNOG	1	0.900	-	-		E1_KOG0127
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I2132
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55464
OrthoDB	1	1.010	-	-		D1181291at2759
OrthoFinder	1	1.000	-	-		FOG0003903
OrthoInspector	1	1.000	-	-		oto18424
orthoMCL	1	0.900	-	-		OOG6_102701
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1976
SonicParanoid	1	1.000	-	-		X2687
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910