Protein Alignment CG4806 and Caper

DIOPT Version :10

• Sequence 1: NP_611955.2
• Gene: CG4806 / 37948
• FlyBaseID: FBgn0260456
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_317010.4
• Gene: Caper / 1277542
• VectorBaseID: AGAMI1_007869
• Length: 595
• Species: Anopheles gambiae
• Alignment Length: 674
• Identity: 135/674 - (20%)
• Similarity: 223/674 - (33%)
• Gaps: 225/674 - (33%)

  Fly   119 FVDWALGKDEYVS-----------------KNPKDEEPD--------------EKKPKVEVKEEN 152
            |.|....|:.::|                 :.|.::|.|              |||.|     ||
Mosquito     6 FYDHETRKEHHISDKMAADDELNNEVLNLLEAPYNKEDDAAASPVENGATTNGEKKSK-----EN 65

  Fly   153 GD-------------EKEVKEESDAEVGKEDESSGE---DSDAESGEDEEDSGESEDEENDEDHK 201
            |.             |:|.:.:.|.|..:|.|...:   |.|.|....:..|| |.....|::.:
Mosquito    66 GHSKSSRHRSRSRERERERERDRDRERDRERERERDRERDRDGEKASKKHRSG-SPGRNRDKERR 129

  Fly   202 ENKDELKSKLDIKNVKREKQISNDVQEGCT-------VFIKNVPFD-------AEDADLRKACRK 252
            .:||..||:...:. .|.|..|.:...|.:       |..|....|       :.:.|.|:..|
Mosquito   130 RSKDRSKSRSPARR-DRSKDRSKEKDRGKSDHHRREVVVEKRRSRDRVDHRRRSRERDYRRRSR- 192

  Fly   253 FGLVSYAIINRQAVSGHSKGTAFVKFK----------------------AKESAD----LCLQAG 291
                     :|....|..:|...:..|                      ::|..|    .|:|..
Mosquito   193 ---------SRDGGRGMGRGRRSMSPKPYRGRGRGGSGYYRDRSPLEEMSQEDRDARTVFCMQLS 248

  Fly   292 TE---------FKLMDEVLDPHPALSREEMKSKQSQENKKDDAKDSRNLYLAREGLIMAGAKAAD 347
            ..         |..:.:|.|.......   |:|:.:.....:.||..::.||   |.::|.|..
Mosquito   249 QRIHARDLEEFFSSVGKVRDVRLITCN---KTKRFKGIAYIEFKDPESVALA---LGLSGQKLL- 306

  Fly   348 GVSASDMAKRHELEQVKTQVLKNLNRFVSR------------NRLSIHNLPQNYDNEKLKQMALT 400
            |:..|   .:|      ||..|  ||..|:            .||.:.:|..|...:.|..:
Mosquito   307 GIPIS---VQH------TQAEK--NRMASQPPVAPPKNPSGPMRLYVGSLHFNITEDMLNGI--- 357

  Fly   401 YTGFRPHECRVMREHKVTPEHPQGKSKGFGFLSFDTHQRALAALRKLNNNPNIFGTQSRPIVAFS 465
               |.|.  ..:...::..:...|:|||:||::|.....|..||.:||.    |....||:...:
Mosquito   358 ---FEPF--GKIDNIQLIMDADTGRSKGYGFITFHNADDAKKALEQLNG----FELAGRPMKVGN 413

  Fly   466 IEDRAVHKIKEKRTERSKQNNPTYQNKQQERKERRQQKRNGQETKTPVPQADNKSKLQKHIKKLE 530
            :.:|.     :..|..|...:              :..|:|.|...       ..:||...|..|
Mosquito   414 VTERL-----DVTTHASLDTD--------------EMDRSGIELGA-------TGRLQLMFKLAE 452

  Fly   531 AS-----RAAKAEGKVAEKKQ-------------------LSDVQGDFVGTAAKPGTSLKMRSKK 571
            .:     ||| |:..:|...|                   ||::...  .|...|...|:::.
Mosquito   453 GAGLAVPRAA-ADALLATAPQPVPQQPIMQSPPIATQCFLLSNMFDP--ATETNPNWDLEIQD-- 512

  Fly   572 KIVEQAKEH--LKKVKTEKRKQ------KNKKIRESHLAERKANNRPKQGRKKETDDLRPLINKY 628
            .::|:..:|  ::.|..:|:..      |...|..:.||....:.|...||......: |||| |
Mosquito   513 DVIEECNKHGGVQHVYVDKQSPSGNVYVKCPSIATAVLAVNALHGRWFAGRVIGAAYV-PLIN-Y 575

  Fly   629 KNMISGNQGGGGVTGGKIKKPKRT 652
            .|:..  :....||   :.:|||:
Mosquito   576 YNLFP--EAAQSVT---MLQPKRS 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4806	NP_611955.2	RRM2_RBM28_like	49..124	CDD:409848	2/4 (50%)
		RRM3_Nop4p	229..312	CDD:410077	18/131 (14%)
		RRM4_RBM28_like	379..468	CDD:409850	22/88 (25%)
		PTZ00121	<473..>622	CDD:173412	31/180 (17%)
Caper	XP_317010.4	None