DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and WHI4

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_010057.1	Gene:	WHI4 / 851302	SGDID:	S000002383	Length:	649	Species:	Saccharomyces cerevisiae

Alignment Length:	406	Identity:	76/406 - (18%)
Similarity:	128/406 - (31%)	Gaps:	107/406 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 DTAKLSRRELAKMRREHTLRALALERELTNKPGQTPASEVLLVRFPDPEITAPMLAGLS------ 152
            :|..||:.....|...::..|:....| ||...:.|..      |....|...||..|:
Yeast    26 ETVPLSKEATYPMPTAYSFSAVRSNSE-TNIKRENPQG------FAKEPIMTSMLHNLTMSTGKG 83

  Fly   153 --KDIRDVVLP--ISVAPRYCLVHLKAGADVEATICDINRVRFGTGHLRAELK-----PFSDEEQ 208
              .|:..:. |  :.|.| |||:......|:....| .......||....|||     ||:|.|:
Yeast    84 NGNDVNSLA-PHDVDVGP-YCLLLRNLPKDITLREC-YCIFSLATGVSSIELKRDDREPFNDNEK 145

  Fly   209 AEFIDPCSLYVGNIPFNMTTSAIKAYFANAM-------------RVDIGVLKREKRARYAFVRYA 260
            ...:...||            ::..::||.:             |..|.|:..:.:...:|..:.
Yeast   146 VVVVKFGSL------------SLVTHYANILNSKSEIFGPSFPFRSHIDVVNEQTQLPVSFQEHV 198

  Fly   261 SPDQTMEAFKELVDSPLNSRTLTVRYRRLRKRAGMPMVQCATSFQALQSPNGDDDNTDCKVISPP 325
            |...|.       .||.|.:..:.....::.::...:....||    .||.|..        :..
Yeast   199 SSGTTN-------SSPKNYQLSSSAQNEIQNQSFNTISYGKTS----SSPLGPS--------AAK 244

  Fly   326 PLESIIISDSDNCSDSSGNGKEDGKRKKKINEQEREIEKLKRQMAEYGAIIKSLQFRQNSLEDTF 390
            |..|::...|...|.:...|.|...::|                       :|:.|.:||:....
Yeast   245 PRPSLLSERSLRFSFNDPFGLETISQRK-----------------------ESVPFLRNSISQHD 286

  Fly   391 IPDLTPKVEPSVNPTGCLLGSNAVHLMRDIKKECDYLGIPDPVPATKPTTQAQDDSQKKAKRSCF 455
            :.::|....|:..|.....|.:.:.|.:|...|..:.|               |:.......|.|
Yeast   287 LSNVTTTPVPAGMPPQKDAGKSLLLLEKDEINESIWNG---------------DELVNDVGNSSF 336

  Fly   456 GRLFTGPFRRGTSAMK 471
            |.....|....|..|:
Yeast   337 GASLQEPPMSSTPVME 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796	18/108 (17%)
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668	12/80 (15%)
WHI4	NP_010057.1	RRM_scw1_like	531..624	CDD:409691
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930