DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and celf1

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_009301602.1	Gene:	celf1 / 58137	ZFINID:	ZDB-GENE-000501-1	Length:	546	Species:	Danio rerio

Alignment Length:	234	Identity:	52/234 - (22%)
Similarity:	74/234 - (31%)	Gaps:	101/234 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 GMPMVQCATSFQALQSP--------NGDDDNTDCKVISPPPLESIIISDSDNCSDSSGNGKEDGK 350
            |.|  ||..|..|::.|        ||..|:.|     .|.::||
Zfish    17 GQP--QCELSLPAVEVPALGGSKKMNGSLDHPD-----QPDIDSI-------------------- 54

  Fly   351 RKKKINEQER--EIEKLKRQMAEYGAIIKSLQFRQNSLEDTFIPDLTPKVEPSVNP---TGC--- 407
             |..:.:..|  ..::|:.....|||:     :..|.|.|.           |.||   .||
Zfish    55 -KMFVGQIPRTWSEDQLRELFEPYGAV-----YEINVLRDR-----------SQNPPQSKGCCFV 102

  Fly   408 --------LLGSNAVHLMRDIKKECDYLGIPDPV---PATKPTTQAQDDSQKKAKRSCFGRLFTG 461
                    |...||:|.|:.:.      |:..|:   ||......|.:|.          :||.|
Zfish   103 TYYTRKSALEAQNALHNMKILP------GMHHPIQMKPADSEKNNAVEDR----------KLFVG 151

  Fly   462 PFRRGTSAMKTADEYEKDDRLE-ELYAQLE-----RDPD 494
            ...:..:        |.|.||. ..|.|:|     |.||
Zfish   152 MISKKCN--------ENDIRLMFSPYGQIEECRILRGPD 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668
celf1	XP_009301602.1	RRM1_CELF1_2_Bruno	53..136	CDD:241075	24/125 (19%)
		ELAV_HUD_SF	56..541	CDD:273741	37/167 (22%)
		RRM2_CELF1_2	145..225	CDD:241078	14/56 (25%)
		RRM3_CELF1_2	454..545	CDD:241082
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579903
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930