DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and Celf3

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_038958836.1	Gene:	Celf3 / 499669	RGDID:	1563168	Length:	526	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	41/224 - (18%)
Similarity:	75/224 - (33%)	Gaps:	59/224 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 TNKPGQTPASEVLLVR----FPDPEITAPMLAGLSKDIRDVVLPISVAPRYCLVHLKAGADVEAT 182
            |...|| ||.:.|...    :||..::|...||.:        ||.......||.|.|.....|.
  Rat   312 TQPTGQ-PAPDALYPNGVHPYPDEALSAERSAGEA--------PIMPQTHSWLVMLSAAQSPAAP 367

  Fly   183 ICDINRVRFGTGHLRA-----------------------------------------ELKPFSDE 206
            :..:.:...|..|..|                                         :.:....:
  Rat   368 VDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQQQQQQQ 432

  Fly   207 EQAEFIDPCSLYVGNIPFNMTTSAIKAY---FANAMRVDIGVLKREKRAR-YAFVRYASPDQTME 267
            :|.|..|.|::::.::|...|.|.|...   |.:.:...:.|.:...::: :.||.:.:|.....
  Rat   433 QQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQA 497

  Fly   268 AFKELVDSPLNSRTLTVRYRRLRKRAGMP 296
            |.:.:....:..:.|.|:.:| .|.|..|
  Rat   498 AIQAMNGFQIGMKRLKVQLKR-PKDANRP 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796	17/94 (18%)
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668	11/71 (15%)
Celf3	XP_038958836.1	RRM1_CELF3_4_5_6	2..88	CDD:410041
		RRM2_CELF3_4_5_6	94..199	CDD:410043
		minC	<242..>376	CDD:178806	18/72 (25%)
		RRM3_CELF3_4_5_6	437..515	CDD:241083	13/77 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340067
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930