DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and bru1

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001260403.1	Gene:	bru1 / 34648	FlyBaseID:	FBgn0000114	Length:	810	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	54/250 - (21%)
Similarity:	94/250 - (37%)	Gaps:	51/250 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 TPAGSQLLPWKTSVDLDND-----AELEKPTSDKKPDTAKLSRRELAKMRREHTLRALA--LERE 120
            |||..|||....:|.|.:.     ..|....|....||:.::...|........|.|:|  .:..
  Fly   581 TPASIQLLQQLQAVGLQHQLLQALTGLGAQQSSSATDTSAVAAAGLLTPMTVQNLAAIAAMTQPS 645

  Fly   121 LTN---------KPG--QTPASEVLLVRFPDPEITAPM--LAGLSKDIRDVVLPISVAPRYCLVH 172
            |:|         .||  |...:..||...|:|..:|.|  .|||.:  ......:|.:| ...|.
  Fly   646 LSNAAAAAAAATSPGSAQLTNTAALLWSDPNPMASAYMSTAAGLPQ--FGSASALSTSP-LASVA 707

  Fly   173 LKAGADVEATICDINRVRFGTGHLRAELKPFSDEEQAEFIDPCSLYVGNIPFNMTTSAIKAY--- 234
            |.|.|...|                        .:|.|..:.|:|::.::|...|.:.:.:.
  Fly   708 LSAAAAAAA------------------------GKQIEGPEGCNLFIYHLPQEFTDTDLASTFLP 748

  Fly   235 FANAMRVDIGVLKREKRAR-YAFVRYASPDQTMEAFKELVDSPLNSRTLTVRYRR 288
            |.|.:...:.:.|:...:: :.||.:.:||....|.|.:....:.::.|.|:.::
  Fly   749 FGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKK 803

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796	17/91 (19%)
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668	13/71 (18%)
bru1	NP_001260403.1	RRM1_CELF1_2_Bruno	356..437	CDD:241075
		ELAV_HUD_SF	359..808	CDD:273741	54/249 (22%)
		RRM2_Bruno_like	443..524	CDD:241080
		RRM3_Bruno_like	722..800	CDD:241084	14/77 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447737
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930