DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and Celf5

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_038934951.1	Gene:	Celf5 / 314647	RGDID:	1565016	Length:	446	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	62/307 - (20%)
Similarity:	104/307 - (33%)	Gaps:	90/307 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 IDPCSLYVGNIPFNMTTSAIKAYFANAMRV-DIGVLKREKRARY---AFVRYASPDQTMEAFKEL 272
            :|...|:||.||.::....:|..|....|: ::.|||......:   ||:.|.:.|..::|...|
  Rat     4 LDAIKLFVGQIPRHLHEQDLKPLFEQFGRIYELTVLKDPHTGVHKGCAFLTYCARDSAIKAQTAL 68

  Fly   273 VDS---PLNSRTLTVRYRRLRKRAG---------MPMVQCATSFQALQSPNGDDDNTDCKVISPP 325
            .:.   |..:|.:.|:......|.|         :...|.......|..|.|..|  :|.|:..|
  Rat    69 HEQKTLPGMARPIQVKPADSENRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVID--ECTVLRGP 131

  Fly   326 PLESIIISDSDNCS---DSS------------GNGKEDGKRKKKI-----NEQEREIEKLKRQMA 370
            .      ..|..|:   .||            |:....|.....:     .::||.:.::::.:.
  Rat   132 D------GSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVG 190

  Fly   371 E--------------YGAIIKSLQFRQNSLEDTFIPDLTPKV--------------------EPS 401
            :              |.|..::|..:|.::..|....|:|.|                    .|.
  Rat   191 QLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGVAFPPCHIQQIGTVSLNGLPATPI 255

  Fly   402 VNPTGC----LLGSNAV-HLMRDIKKECDYLGIPD--PVPATKPTTQ 441
            ...:|.    |||:.|| .||..|..     |.|.  |.|.:.|..:
  Rat   256 APASGLHSPPLLGTAAVPGLMTSIPS-----GFPGVLPFPGSHPALE 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796	21/86 (24%)
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668	19/74 (26%)
Celf5	XP_038934951.1	RRM1_CELF3_4_5_6	2..88	CDD:410041	21/83 (25%)
		PABP-1234	<9..358	CDD:130689	61/302 (20%)
		RRM2_CELF3_4_5_6	95..175	CDD:410043	14/87 (16%)
		RRM3_CELF3_4_5_6	357..435	CDD:241083
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930