DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and Celf4

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_038952808.1	Gene:	Celf4 / 307540	RGDID:	1307630	Length:	583	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	45/252 - (17%)
Similarity:	81/252 - (32%)	Gaps:	90/252 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 PFSDEEQAEFIDPCSLYVGNIPFNMTTSAIKAYFANAMRV-DIGVLKREKRARY---AFVRYASP 262
            |..|.      |...|::|.||.|:....:|..|....:: ::.|||......:   ||:.|...
  Rat    47 PMKDH------DAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCER 105

  Fly   263 DQTMEAFKELVDS---PLNSRTLTVRYRRLRKRAG-----MPMVQCATSFQALQSPNGDDDNT-- 317
            :..::|...|.:.   |..:|.:.|:......|.|     .|..|....|..:.:....:|:.
  Rat   106 ESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRR 170

  Fly   318 ---------DCKVISPPPLESIIISDSDNCSDSSGNGK--------EDGKRKKKIN--------- 356
                     :|.::..|                .||.|        ...:.:..||
  Rat   171 LFEAFGNIEECTILRGP----------------DGNSKGCAFVKYSSHAEAQAAINALHGSQTMP 219

  Fly   357 -------------EQEREIEKLKRQMA--------------EYGAIIKSLQFRQNSL 386
                         ::||.:.:: :|||              .|||..::|..:|.:|
  Rat   220 GASSSLVVKFADTDKERTMRRM-QQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAAL 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796	21/96 (22%)
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668	17/74 (23%)
Celf4	XP_038952808.1	RRM1_CELF3_4_5_6	49..135	CDD:410041	20/91 (22%)
		PABP-1234	<56..378	CDD:130689	42/237 (18%)
		RRM2_CELF3_4_5_6	151..231	CDD:410043	9/95 (9%)
		RRM_SF	417..>465	CDD:418427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930