DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and Celf2

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_038951514.1	Gene:	Celf2 / 29428	RGDID:	68347	Length:	546	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	45/235 - (19%)
Similarity:	83/235 - (35%)	Gaps:	60/235 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 PDTAKLSRRELAKMRREHTLRALALERELTNKPGQTPASEVLLVRFPDPEITAPMLAGLSKDIRD 157
            ||..|:...::.:...|..|      :||....|......||..|..:|    |...|.
  Rat    65 PDAIKMFVGQIPRSWSEKEL------KELFEPYGAVYQINVLRDRSQNP----PQSKGC------ 113

  Fly   158 VVLPISVAPRYCLVHL---KAGADVEATICDINRVRFGTG-HLRAELKPFSDEEQAEFIDPCSLY 218
                       |.|..   ||..:.:..:.:|..:   .| |...::|| :|.|::..::...|:
  Rat   114 -----------CFVTFYTRKAALEAQNALHNIKTL---PGMHHPIQMKP-ADSEKSNAVEDRKLF 163

  Fly   219 VGNIPFNMTTSAIKAYFANAMRVDIGVLKREKRAR--------YAFVRYASPDQTMEAFKELVDS 275
            :|.:......:.|:..|:     ..|.::..:..|        .|||.:::......|.|.:..|
  Rat   164 IGMVSKKCNENDIRVMFS-----PFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQS 223

  Fly   276 PLN---SRTLTVRY---------RRLRKRAGMPMVQCATS 303
            ...   |..:.|::         |||:::....|.|..|:
  Rat   224 QTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTA 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796	21/110 (19%)
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668	13/78 (17%)
Celf2	XP_038951514.1	RRM1_CELF1_2_Bruno	67..150	CDD:410040	21/113 (19%)
		RRM2_CELF1_2	159..239	CDD:410042	14/84 (17%)
		RRM3_CELF1_2	454..545	CDD:241082
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930