DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pof and Celf2

DIOPT Version :9

Sequence 1:	NP_001246498.1	Gene:	Pof / 37947	FlyBaseID:	FBgn0035047	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_030103179.1	Gene:	Celf2 / 14007	MGIID:	1338822	Length:	536	Species:	Mus musculus

Alignment Length:	267	Identity:	51/267 - (19%)
Similarity:	95/267 - (35%)	Gaps:	72/267 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 KTSVDLDN-DAELEKPTSDK-----------KPDTAKLSRRELAKMRREHTLRALALERELTNKP 125
            |::|.:.| :..|...|::|           .||..|:...::.:...|..|      :||....
Mouse    23 KSAVTMRNEELLLSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKEL------KELFEPY 81

  Fly   126 GQTPASEVLLVRFPDPEITAPMLAGLSKDIRDVVLPISVAPRYCLVHL---KAGADVEATICDIN 187
            |......||..|..:|    |...|.                 |.|..   ||..:.:..:.:|.
Mouse    82 GAVYQINVLRDRSQNP----PQSKGC-----------------CFVTFYTRKAALEAQNALHNIK 125

  Fly   188 RVRFGTG-HLRAELKPFSDEEQAEFIDPCSLYVGNIPFNMTTSAIKAYFANAMRVDIGVLKREKR 251
            .:   .| |...::|| :|.|::..::...|::|.:......:.|:..|:     ..|.::..:.
Mouse   126 TL---PGMHHPIQMKP-ADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFS-----PFGQIEECRI 181

  Fly   252 AR--------YAFVRYASPDQTMEAFKELVDSPLN---SRTLTVRY---------RRLRKRAGMP 296
            .|        .|||.:::......|.|.:..|...   |..:.|::         |||:::....
Mouse   182 LRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQ 246

  Fly   297 MVQCATS 303
            |.|..|:
Mouse   247 MQQLNTA 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_001246498.1	RRM	<201..>292	CDD:223796	21/110 (19%)
Pof	NP_001246498.1	RRM_SF	217..285	CDD:240668	13/78 (17%)
Celf2	XP_030103179.1	RRM1_CELF1_2_Bruno	57..140	CDD:241075	21/113 (19%)
		RRM2_CELF1_2	149..229	CDD:241078	14/84 (17%)
		RRM3_CELF1_2	444..535	CDD:241082
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836399
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930