Protein Alignment Pof and CELF1

DIOPT Version :10

• Sequence 1: NP_523851.1
• Gene: Pof / 37947
• FlyBaseID: FBgn0035047
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001317201.1
• Gene: CELF1 / 10658
• HGNCID: 2549
• Length: 514
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 62/324 - (19%)
• Similarity: 114/324 - (35%)
• Gaps: 116/324 - (35%)

  Fly   139 PD-PEITA-PMLAG------LSKDIRDV------VLPISV----------APRYCLVHL---KAG 176
            || |::.| .|..|      ..||:|::      |..|:|          :...|.|..   ||.
Human    35 PDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAA 99

  Fly   177 ADVEATICDINRVRFGTGHLRAELKPFSDEEQAEFIDPCSLYVGNIPFNMTTSAIKAYFANAMRV 241
            .:.:..:.:: :|..|..| ..::|| :|.|:...::...|::|.|....|.:.|:..|::..::
Human   100 LEAQNALHNM-KVLPGMHH-PIQMKP-ADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQI 161

  Fly   242 DIGVLKREKRARYAFVRYASPDQTME--AFKELVDSPLNSRTLTVRYRRLRKRAGMPMVQCATSF 304
            :...:.|            .||....  ||            :|...|.:.:.|...|.| |.:.
Human   162 EECRILR------------GPDGLSRGCAF------------VTFTTRAMAQTAIKAMHQ-AQTM 201

  Fly   305 QALQSPNGDDDNTDCKVISPPPLESIIISDSDNCSDSSGNGKEDGKRKKKINEQEREIEKLKRQM 369
            :...||                   :::..:|.               :|..||:|..::|::||
Human   202 EGCSSP-------------------MVVKFADT---------------QKDKEQKRMAQQLQQQM 232

  Fly   370 AEYGA-----------------IIKSLQFRQNSLEDTFIPDLTPKVEPSVNPTGCLLGSNAVHL 416
            .:..|                 :...||..|.:.....:..|:     |::|.|   |.||:.|
Human   233 QQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLS-----SLHPMG---GLNAMQL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pof	NP_523851.1	RRM_SF	217..285	CDD:409669	12/69 (17%)
CELF1	NP_001317201.1	RRM1_CELF1_2_Bruno	42..125	CDD:410040	18/85 (21%)
		RRM2_CELF1_2	134..214	CDD:410042	19/123 (15%)
		RRM3_CELF1_2	422..513	CDD:241082