DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-19 and Ndufa8

DIOPT Version :9

Sequence 1:	NP_001163296.1	Gene:	ND-19 / 37946	FlyBaseID:	FBgn0035046	Length:	175	Species:	Drosophila melanogaster
Sequence 2:	NP_080979.1	Gene:	Ndufa8 / 68375	MGIID:	1915625	Length:	172	Species:	Mus musculus

Alignment Length:	164	Identity:	75/164 - (45%)
Similarity:	99/164 - (60%)	Gaps:	4/164 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LPEESELNVQELNLSSAALRAGAFHLGKQCEQANNEFMLCRQELDDPRACLAEGKAVTSCALDFF 73
            ||...||.|:|:.:|||.|:|.|.|.|.||::.|.||||||.|..|||.||.|||.|..|||:||
Mouse     7 LPTLEELKVEEVKVSSAVLKAAAHHYGAQCDKTNKEFMLCRWEEKDPRRCLKEGKLVNGCALNFF 71

  Fly    74 RKVKKTCHEEFTQYATCLDKSSGTMAFSHCRKTQGVFDKCIKDNFDWDRPSYGYFSRAKVIQSAR 138
            |::|..|.|.||:|.||||.|: ...|.|||:.|..||:|:.|...|.||..|..|:...:::.|
Mouse    72 RQIKSHCAEPFTEYWTCLDYSN-MQLFRHCRQQQAKFDQCVLDKLGWVRPDLGQLSKVTKVKTDR 135

  Fly   139 EAPKKE-EKVSYPDATPGLPEDYPKPPAKYGSRF 171
            ..|:.. ...:.|:..|.:..|.  .|||:|:||
Mouse   136 PLPENPYHSRARPEPNPVIEGDL--KPAKHGTRF 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-19	NP_001163296.1	CHCH	80..116	CDD:399611	18/35 (51%)
Ndufa8	NP_080979.1	Cx9C motif 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	36..46		5/9 (56%)
		Cx9C motif 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	56..66		6/9 (67%)
		CHCH	78..111	CDD:399611	17/33 (52%)
		Cx9C motif 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	78..88		5/9 (56%)
		Cx9C motif 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	100..110		5/9 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850734
Domainoid	1	1.000	87	1.000	Domainoid score	I8016
eggNOG	1	0.900	-	-		E1_KOG3458
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40932
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4384
Isobase	1	0.950	-	0	Normalized mean entropy	S4539
OMA	1	1.010	-	-		QHG45925
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005263
OrthoInspector	1	1.000	-	-		oto95375
orthoMCL	1	0.900	-	-		OOG6_103954
Panther	1	1.100	-	-	LDO	PTHR13344
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4238
SonicParanoid	1	1.000	-	-		X4877
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740