DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3663 and ISOC1

DIOPT Version :9

Sequence 1:	NP_611952.1	Gene:	CG3663 / 37944	FlyBaseID:	FBgn0035044	Length:	208	Species:	Drosophila melanogaster
Sequence 2:	NP_057132.2	Gene:	ISOC1 / 51015	HGNCID:	24254	Length:	298	Species:	Homo sapiens

Alignment Length:	181	Identity:	81/181 - (44%)
Similarity:	124/181 - (68%)	Gaps:	6/181 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 HLNPKKTLFLLCDIQEKFRPAMPLFDNMIKNVDKLTRAGKALDVPLIVTEHYPEKLGKTVAQLDV 71
            :|.|..|:|..||:||:||||:..|.::|....:|.:..:.|.:|:||||.||:.||.||.::|:
Human   109 NLTPSSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVIVTEQYPKGLGSTVQEIDL 173

  Fly    72 SHAKLVSGKTLFSMFTPEVKAVIKDIFNDKP--EDVVLYGLESHICVEQTAIDLLEQNINVYIVA 134
            :..|||..||.|||..|||:|.:.:|    |  ..|||:|:|:|:|::|||::|:.:.:.|:|||
Human   174 TGVKLVLPKTKFSMVLPEVEAALAEI----PGVRSVVLFGVETHVCIQQTALELVGRGVEVHIVA 234

  Fly   135 DCCSSRLNQDRDLALDRLRQAGCVITTSESVIFDLVRDKNNPKFDVVRKLV 185
            |..|||...||..||:||.:.|.::||||:|:..||.||::|||..::.|:
Human   235 DATSSRSMMDRMFALERLARTGIIVTTSEAVLLQLVADKDHPKFKEIQNLI 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3663	NP_611952.1	YcaC_related	14..171	CDD:238494	71/158 (45%)
ISOC1	NP_057132.2	YcaC_related	116..270	CDD:238494	70/157 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143760
Domainoid	1	1.000	140	1.000	Domainoid score	I4758
eggNOG	1	0.900	-	-		E1_COG1335
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H9361
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4185
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54144
OrthoDB	1	1.010	-	-		D1100720at2759
OrthoFinder	1	1.000	-	-		FOG0001690
OrthoInspector	1	1.000	-	-		mtm8500
orthoMCL	1	0.900	-	-		OOG6_101675
Panther	1	1.100	-	-	LDO	PTHR14119
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1084
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770