DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4781 and lrrc4.1

DIOPT Version :9

Sequence 1:NP_611951.1 Gene:CG4781 / 37943 FlyBaseID:FBgn0035043 Length:469 Species:Drosophila melanogaster
Sequence 2:XP_005164844.1 Gene:lrrc4.1 / 565021 ZFINID:ZDB-GENE-041210-129 Length:858 Species:Danio rerio


Alignment Length:420 Identity:104/420 - (24%)
Similarity:166/420 - (39%) Gaps:88/420 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MARLEVIRGLTFALLLTQLLAAHVARAEVIDAEETDRFCYPESSKNSRRSCECSNVSASPWGNRA 65
            :.|:.|.|....|||....|... |..||:.|         ...:.....|.|:        |:.
Zfish     8 LGRVAVRRARKAALLCVLFLMVQ-ACVEVVAA---------AGPQGCPTDCSCN--------NQL 54

  Fly    66 LRIDCSYKDYKVADLSLLLPLYIDSLDLSWNALDSVPIFTSDSLHQ---LNLRHNNISQLVSGNF 127
            .::.|:.:.  :..:...:|.....|:|..||::||.:.:..:||.   |.|..|.|.|:..|.|
Zfish    55 SKVVCTRRG--LTRVPPGIPSTTRHLNLMENAIESVQVDSFRNLHHLEVLQLGRNAIRQIEVGAF 117

  Fly   128 KQLTSLRELYLGWNSIGKLESGSFDGLPHLQVLDLAHNNLHLLPGHLFAPLLVLGTLDISWNRRF 192
            ..||:|..|.|..|.:..:.||:|:.|..|:.|.|.:|.:..:|.:.|..:..|..||:...|:.
Zfish   118 SGLTNLNTLELFDNRLTVVPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELRKL 182

  Fly   193 NESGGDLYTGLGVNWKLSTLRLDACSLNDLHLPVNAPLKELSLRRNQLKRIPTQLPETLLRLDIS 257
            .......:.|| ||  |..|.|..|::.. .:|...||..|.                  .|:||
Zfish   183 EYISDGAFEGL-VN--LKYLNLGMCNIRG-EMPNFTPLVGLE------------------ELEIS 225

  Fly   258 DNLLEELLPEDTANLTQVRQLFIEDMPVLQRVVANSLTHVDVLETLSFQNSRQLSHLDAEAFGPI 322
            :||..|:.|.....|:.:::|:|.:..:       .|...:..:.|:......|:|.:..:....
Zfish   226 ENLFPEIKPGSFRGLSSLKKLWIMNSQI-------GLIERNAFDDLASLVELNLAHNNLSSLPHD 283

  Fly   323 MTTPTKKRALRSLSFRGTMLRTFNSTLAPIFTQLAELDLNGLPLQCDCELVWL-----KQLPVQT 382
            :.||.|                          .|.||.|:..|..|.|:.:||     :.:|..:
Zfish   284 LYTPLK--------------------------YLVELHLHHNPWNCGCDSLWLARWLREYIPTNS 322

  Fly   383 N--GRCYKPARIRG-MLVTSARGD--AFSC 407
            .  |||:.||.:|| .||...|||  |..|
Zfish   323 TCCGRCHSPAHMRGRQLVELDRGDTGAMQC 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4781NP_611951.1 leucine-rich repeat 90..108 CDD:275380 6/17 (35%)
LRR_8 108..167 CDD:290566 23/61 (38%)
leucine-rich repeat 109..132 CDD:275380 10/25 (40%)
LRR_RI <121..>261 CDD:238064 39/139 (28%)
leucine-rich repeat 133..156 CDD:275380 8/22 (36%)
leucine-rich repeat 157..180 CDD:275380 6/22 (27%)
leucine-rich repeat 181..208 CDD:275380 8/26 (31%)
leucine-rich repeat 230..253 CDD:275380 2/22 (9%)
leucine-rich repeat 254..274 CDD:275380 8/19 (42%)
leucine-rich repeat 275..299 CDD:275380 3/23 (13%)
leucine-rich repeat 300..319 CDD:275380 3/18 (17%)
lrrc4.1XP_005164844.1 LRRNT 43..77 CDD:214470 5/43 (12%)
leucine-rich repeat 54..73 CDD:275380 1/20 (5%)
leucine-rich repeat 75..98 CDD:275380 7/22 (32%)
LRR_8 76..133 CDD:290566 21/56 (38%)
LRR_RI 93..323 CDD:238064 68/284 (24%)
leucine-rich repeat 99..122 CDD:275380 8/22 (36%)
LRR_8 121..206 CDD:290566 27/87 (31%)
leucine-rich repeat 123..146 CDD:275380 8/22 (36%)
leucine-rich repeat 147..170 CDD:275380 6/22 (27%)
leucine-rich repeat 171..195 CDD:275380 6/24 (25%)
leucine-rich repeat 196..218 CDD:275380 7/22 (32%)
LRR_8 218..277 CDD:290566 15/83 (18%)
leucine-rich repeat 219..242 CDD:275380 9/40 (23%)
leucine-rich repeat 243..266 CDD:275380 4/29 (14%)
leucine-rich repeat 267..288 CDD:275380 3/20 (15%)
IG_like 361..443 CDD:214653
Ig 372..443 CDD:299845
STOP 616..799 CDD:283000
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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