DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4781 and lrrc4cb

DIOPT Version :9

Sequence 1:NP_611951.1 Gene:CG4781 / 37943 FlyBaseID:FBgn0035043 Length:469 Species:Drosophila melanogaster
Sequence 2:XP_005166545.1 Gene:lrrc4cb / 564462 ZFINID:ZDB-GENE-080327-5 Length:631 Species:Danio rerio


Alignment Length:432 Identity:100/432 - (23%)
Similarity:156/432 - (36%) Gaps:120/432 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 EVIRG----------LTFALLLTQLL-AAHVARAEVIDAEETDRFCYPESSKNSRRSCECSNVSA 58
            :::||          |...||..||| .|.:.||:...:                 .|.||    
Zfish    12 QMLRGPRWKGAWFDPLFLLLLALQLLVVAGLVRAQTCPS-----------------VCSCS---- 55

  Fly    59 SPWGNRALRIDCSYKDYKVADLSLLLPLYIDSLDLSWNALDSVPIFTSDSLHQLNLRHNNISQLV 123
                |:..::.|:.:                       .|..||...|.:...|||:.|.|..:.
Zfish    56 ----NQFSKVICTRR-----------------------GLKDVPDGVSTNTRYLNLQDNQIQVIK 93

  Fly   124 SGNFKQLTSLRELYLGWNSIGKLESGSFDGLPHLQVLDLAHNNLHLLPGHLFAPLLVLGTLDISW 188
            ..:||.|..|..|.|..|.|..:|.|:|:||..|..|:|..|.|..:|...|..|..|..|   |
Zfish    94 VDSFKHLRHLEILQLSRNHIRNIEIGAFNGLTSLNTLELFDNRLTTIPNGAFEYLSKLKEL---W 155

  Fly   189 --NRRFNESGGDLYTGLGVNWKLSTLRLDACSLNDL-HLPVNA-----PLKELSLRRNQLKRIPT 245
              |........|.::.|.     |..|||...|..| ::...|     .|:.|:|....||.:|.
Zfish   156 LRNNPIESIPSDAFSRLP-----SLRRLDLGELKRLSYISSGAFQGLSNLRYLNLGMCNLKEVPN 215

  Fly   246 QLPETLLRLD---ISDNLLEELLPEDTANLTQVRQLFIEDMPVLQRVVANSLTHVDVLETLSFQN 307
            ..|  |:|||   :|.|.|..:.|.....|..:::|::....| |.:..||...:..|..|:..:
Zfish   216 IQP--LIRLDELEMSGNQLTVIQPSSFKGLVHLQKLWMMHAQV-QTIERNSFDDLHSLRELNLAH 277

  Fly   308 SRQLSHLDAEAFGPIMTTPTKKRALRSLSFRGTMLRTFNSTLAPIFTQLAELDLNGLPLQCDCEL 372
            : .|:.|..:.:.|:                               ..|..:.|:..|..|:|::
Zfish   278 N-NLTFLPHDLYTPL-------------------------------HHLQRVHLHHNPWNCNCDI 310

  Fly   373 VWL-----KQLPVQTN--GRCYKPARIRGMLVTSARGDAFSC 407
            :||     :.:|..|:  .||..|..::|..:.......|.|
Zfish   311 LWLSWWLRETVPTNTSCCARCNSPPSLKGRYIGELDQSYFQC 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4781NP_611951.1 leucine-rich repeat 90..108 CDD:275380 4/17 (24%)
LRR_8 108..167 CDD:290566 22/58 (38%)
leucine-rich repeat 109..132 CDD:275380 8/22 (36%)
LRR_RI <121..>261 CDD:238064 47/150 (31%)
leucine-rich repeat 133..156 CDD:275380 10/22 (45%)
leucine-rich repeat 157..180 CDD:275380 8/22 (36%)
leucine-rich repeat 181..208 CDD:275380 6/28 (21%)
leucine-rich repeat 230..253 CDD:275380 8/22 (36%)
leucine-rich repeat 254..274 CDD:275380 7/22 (32%)
leucine-rich repeat 275..299 CDD:275380 5/23 (22%)
leucine-rich repeat 300..319 CDD:275380 4/18 (22%)
lrrc4cbXP_005166545.1 LRRNT 48..81 CDD:214470 9/80 (11%)
LRR_8 77..137 CDD:290566 22/59 (37%)
leucine-rich repeat 79..102 CDD:275380 8/22 (36%)
LRR_RI 82..>281 CDD:238064 62/210 (30%)
leucine-rich repeat 103..126 CDD:275380 10/22 (45%)
LRR_8 125..180 CDD:290566 17/62 (27%)
leucine-rich repeat 127..150 CDD:275380 8/22 (36%)
leucine-rich repeat 151..174 CDD:275380 6/30 (20%)
leucine-rich repeat 175..199 CDD:275380 6/23 (26%)
leucine-rich repeat 200..221 CDD:275380 8/22 (36%)
LRR_8 221..280 CDD:290566 15/60 (25%)
leucine-rich repeat 222..245 CDD:275380 7/22 (32%)
leucine-rich repeat 246..269 CDD:275380 5/23 (22%)
leucine-rich repeat 270..291 CDD:275380 4/21 (19%)
LRRCT 302..352 CDD:214507 12/49 (24%)
I-set 355..443 CDD:254352
Ig 372..439 CDD:143165
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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