DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4781 and 18w

DIOPT Version :9

Sequence 1:NP_611951.1 Gene:CG4781 / 37943 FlyBaseID:FBgn0035043 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_476814.1 Gene:18w / 37277 FlyBaseID:FBgn0004364 Length:1385 Species:Drosophila melanogaster


Alignment Length:452 Identity:109/452 - (24%)
Similarity:155/452 - (34%) Gaps:163/452 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 LDLSWNALDSVPIFTSD-----SLHQLNLRHNNISQLVSGNFKQLTSLRELYLGWNSIGKLESGS 150
            ||||.|.|.|..:..|.     .|..|||.:|.::::.|..||:|..|:.|.:..||||.:|.|:
  Fly   312 LDLSGNQLTSHHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGA 376

  Fly   151 FDGLPHLQVLDLAHNNLHLLPGHLFAPLLVLGTLDISWNRRFNESGGDLYTGLGVNWKLSTLRLD 215
            |..|.:|..|:||.|.||              |||   ||.||        ||.|..|| ||..:
  Fly   377 FLPLYNLHTLNLAENRLH--------------TLD---NRIFN--------GLYVLTKL-TLNNN 415

  Fly   216 ACSLNDLHLPVN-APLKELSLRRNQLKRIPTQLPE--TLLRLDISDNLLEELLPEDTANLTQVRQ 277
            ..|:.:.....| :.||||.|..|||..:|..:.:  .|..||:.:|.:.|.......||.|:..
  Fly   416 LVSIVESQAFRNCSDLKELDLSSNQLTEVPEAVQDLSMLKTLDLGENQISEFKNNTFRNLNQLTG 480

  Fly   278 L-------------FIEDMPVLQ--------------------------RVVANSLT-------- 295
            |             ..:|:|.|.                          |:..|.||        
  Fly   481 LRLIDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIERGAFDKNTEIEAIRLDKNFLTDINGIFAT 545

  Fly   296 -------------------------------HVDVLETL-------------------------- 303
                                           |.:.:|.|                          
  Fly   546 LASLLWLNLSENHL
VWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVTTLDASHNRITEIG 610

  Fly   304 --SFQNSRQLSHLDAEAFGPIM-TTPTKKRALRSLSFRGTMLRTFNST---LAPIFTQ--LAELD 360
              |..||.:|..::....|.|. .|...|..|..:.....:|...:..   :||:..:  :.|..
  Fly   611 AMSVPNSIELLFINNNIIGQIQANTFVDKTRLARVDLYANVLSKISLNALRVAPVSAEKPVPEFY 675

  Fly   361 LNGLPLQCDCELVWLKQLPVQT-----------NGRCYKP----ARIRGMLVTSARGDAFSC 407
            |.|.|.:|||.:.||:::...|           |..|..|    |.:|.:...||  ..|.|
  Fly   676 LGGNPFECDCSMEWLQRINNLTTRQHPHVVDLGNIECLMPHSRSAPLRPLASLSA--SDFVC 735

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4781NP_611951.1 leucine-rich repeat 90..108 CDD:275380 8/21 (38%)
LRR_8 108..167 CDD:290566 24/58 (41%)
leucine-rich repeat 109..132 CDD:275380 9/22 (41%)
LRR_RI <121..>261 CDD:238064 50/142 (35%)
leucine-rich repeat 133..156 CDD:275380 10/22 (45%)
leucine-rich repeat 157..180 CDD:275380 7/22 (32%)
leucine-rich repeat 181..208 CDD:275380 10/26 (38%)
leucine-rich repeat 230..253 CDD:275380 10/24 (42%)
leucine-rich repeat 254..274 CDD:275380 6/19 (32%)
leucine-rich repeat 275..299 CDD:275380 9/101 (9%)
leucine-rich repeat 300..319 CDD:275380 6/46 (13%)
18wNP_476814.1 leucine-rich repeat 66..91 CDD:275380
leucine-rich repeat 92..115 CDD:275380
LRR_8 115..181 CDD:290566
leucine-rich repeat 116..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..201 CDD:275380
LRR_RI 210..464 CDD:238064 63/177 (36%)
leucine-rich repeat 212..236 CDD:275380
LRR_8 235..295 CDD:290566
leucine-rich repeat 237..260 CDD:275380
leucine-rich repeat 261..284 CDD:275380
LRR_8 283..345 CDD:290566 13/32 (41%)
leucine-rich repeat 285..308 CDD:275380
leucine-rich repeat 309..334 CDD:275380 8/21 (38%)
LRR_8 334..393 CDD:290566 24/58 (41%)
leucine-rich repeat 335..358 CDD:275380 9/22 (41%)
leucine-rich repeat 359..382 CDD:275380 10/22 (45%)
LRR_8 382..441 CDD:290566 29/84 (35%)
leucine-rich repeat 383..406 CDD:275380 16/47 (34%)
leucine-rich repeat 407..430 CDD:275380 6/23 (26%)
LRR_8 431..488 CDD:290566 18/56 (32%)
leucine-rich repeat 431..451 CDD:275380 9/19 (47%)
leucine-rich repeat 454..477 CDD:275380 7/22 (32%)
LRR_8 477..559 CDD:290566 9/81 (11%)
leucine-rich repeat 478..499 CDD:275380 1/20 (5%)
leucine-rich repeat 502..525 CDD:275380 1/22 (5%)
leucine-rich repeat 526..548 CDD:275380 4/21 (19%)
leucine-rich repeat 590..617 CDD:275380 1/26 (4%)
leucine-rich repeat 618..641 CDD:275380 5/22 (23%)
leucine-rich repeat 642..689 CDD:275380 11/46 (24%)
LRRCT 679..736 CDD:214507 16/59 (27%)
leucine-rich repeat 775..796 CDD:275380
LRR_8 797..852 CDD:290566
leucine-rich repeat 797..817 CDD:275380
leucine-rich repeat 818..841 CDD:275380
LRR_8 841..900 CDD:290566
leucine-rich repeat 842..865 CDD:275380
LRR_4 866..907 CDD:289563
leucine-rich repeat 866..889 CDD:275380
leucine-rich repeat 890..911 CDD:275380
TIR 1045..1183 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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