Protein Alignment CG4781 and 18w

DIOPT Version :10

• Sequence 1: NP_611951.1
• Gene: CG4781 / 37943
• FlyBaseID: FBgn0035043
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_476814.1
• Gene: 18w / 37277
• FlyBaseID: FBgn0287775
• Length: 1385
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 109/452 - (24%)
• Similarity: 155/452 - (34%)
• Gaps: 163/452 - (36%)

  Fly    91 LDLSWNALDSVPIFTSD-----SLHQLNLRHNNISQLVSGNFKQLTSLRELYLGWNSIGKLESGS 150
            ||||.|.|.|..:..|.     .|..|||.:|.::::.|..||:|..|:.|.:..||||.:|.|:
  Fly   312 LDLSGNQLTSHHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGA 376

  Fly   151 FDGLPHLQVLDLAHNNLHLLPGHLFAPLLVLGTLDISWNRRFNESGGDLYTGLGVNWKLSTLRLD 215
            |..|.:|..|:||.|.||              |||   ||.||        ||.|..|| ||..:
  Fly   377 FLPLYNLHTLNLAENRLH--------------TLD---NRIFN--------GLYVLTKL-TLNNN 415

  Fly   216 ACSLNDLHLPVN-APLKELSLRRNQLKRIPTQLPE--TLLRLDISDNLLEELLPEDTANLTQVRQ 277
            ..|:.:.....| :.||||.|..|||..:|..:.:  .|..||:.:|.:.|.......||.|:..
  Fly   416 LVSIVESQAFRNCSDLKELDLSSNQLTEVPEAVQDLSMLKTLDLGENQISEFKNNTFRNLNQLTG 480

  Fly   278 L-------------FIEDMPVLQ--------------------------RVVANSLT-------- 295
            |             ..:|:|.|.                          |:..|.||
  Fly   481 LRLIDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIERGAFDKNTEIEAIRLDKNFLTDINGIFAT 545

  Fly   296 -------------------------------HVDVLETL-------------------------- 303
                                           |.:.:|.|
  Fly   546 LASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVTTLDASHNRITEIG 610

  Fly   304 --SFQNSRQLSHLDAEAFGPIM-TTPTKKRALRSLSFRGTMLRTFNST---LAPIFTQ--LAELD 360
              |..||.:|..::....|.|. .|...|..|..:.....:|...:..   :||:..:  :.|..
  Fly   611 AMSVPNSIELLFINNNIIGQIQANTFVDKTRLARVDLYANVLSKISLNALRVAPVSAEKPVPEFY 675

  Fly   361 LNGLPLQCDCELVWLKQLPVQT-----------NGRCYKP----ARIRGMLVTSARGDAFSC 407
            |.|.|.:|||.:.||:::...|           |..|..|    |.:|.:...||  ..|.|
  Fly   676 LGGNPFECDCSMEWLQRINNLTTRQHPHVVDLGNIECLMPHSRSAPLRPLASLSA--SDFVC 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4781	NP_611951.1	LRR	<90..367	CDD:443914	94/395 (24%)
		leucine-rich repeat	90..108	CDD:275380	8/21 (38%)
		leucine-rich repeat	109..132	CDD:275380	9/22 (41%)
		leucine-rich repeat	133..156	CDD:275380	10/22 (45%)
		leucine-rich repeat	157..180	CDD:275380	7/22 (32%)
		leucine-rich repeat	181..208	CDD:275380	10/26 (38%)
		leucine-rich repeat	230..253	CDD:275380	10/24 (42%)
		leucine-rich repeat	254..274	CDD:275380	6/19 (32%)
		leucine-rich repeat	275..299	CDD:275380	9/101 (9%)
		leucine-rich repeat	300..319	CDD:275380	6/46 (13%)
18w	NP_476814.1	leucine-rich repeat	66..91	CDD:275380
		leucine-rich repeat	92..115	CDD:275380
		LRR_8	115..181	CDD:404697
		leucine-rich repeat	116..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..201	CDD:275380
		LRR	210..592	CDD:443914	78/305 (26%)
		leucine-rich repeat	212..236	CDD:275380
		leucine-rich repeat	237..260	CDD:275380
		leucine-rich repeat	261..284	CDD:275380
		leucine-rich repeat	285..308	CDD:275380
		leucine-rich repeat	309..334	CDD:275380	8/21 (38%)
		leucine-rich repeat	335..358	CDD:275380	9/22 (41%)
		leucine-rich repeat	359..382	CDD:275380	10/22 (45%)
		leucine-rich repeat	383..406	CDD:275380	16/47 (34%)
		leucine-rich repeat	407..430	CDD:275380	6/23 (26%)
		leucine-rich repeat	431..451	CDD:275380	9/19 (47%)
		leucine-rich repeat	454..477	CDD:275380	7/22 (32%)
		leucine-rich repeat	478..499	CDD:275380	1/20 (5%)
		leucine-rich repeat	502..525	CDD:275380	1/22 (5%)
		leucine-rich repeat	526..548	CDD:275380	4/21 (19%)
		leucine-rich repeat	590..617	CDD:275380	1/26 (4%)
		leucine-rich repeat	618..641	CDD:275380	5/22 (23%)
		leucine-rich repeat	642..689	CDD:275380	11/46 (24%)
		LRRCT	679..736	CDD:214507	16/59 (27%)
		LRR	<775..>920	CDD:443914
		leucine-rich repeat	775..796	CDD:275380
		leucine-rich repeat	797..817	CDD:275380
		leucine-rich repeat	818..841	CDD:275380
		leucine-rich repeat	842..865	CDD:275380
		leucine-rich repeat	866..889	CDD:275380
		leucine-rich repeat	890..911	CDD:275380
		TIR	1045..1183	CDD:214587