Protein Alignment CG4781 and Lrrc4c

DIOPT Version :10

• Sequence 1: NP_611951.1
• Gene: CG4781 / 37943
• FlyBaseID: FBgn0035043
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_848840.3
• Gene: Lrrc4c / 241568
• MGIID: 2442636
• Length: 640
• Species: Mus musculus
• Alignment Length: 428
• Identity: 101/428 - (23%)
• Similarity: 153/428 - (35%)
• Gaps: 133/428 - (31%)

  Fly    10 LTFALLLTQLLAAHVARAEVIDAEETDRFCYPESSKNSRRSCECSNVSASPWGNRALRIDCSYKD 74
            |...|.|..|:.|.:.||:...:                 .|.||        |:..::.|..|:
Mouse    27 LVVLLALQLLVVAGLVRAQTCPS-----------------VCSCS--------NQFSKVICVRKN 66

  Fly    75 YKVADLSLLLPLYIDSLDLSWNALDSVPIFTSDSLHQLNLRHNNISQLVSGNFKQLTSLRELYLG 139
                                   |..||...|.:...|||..|.|..:...:||.|..|..|.|.
Mouse    67 -----------------------LREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLS 108

  Fly   140 WNSIGKLESGSFDGLPHLQVLDLAHNNLHLLPGHLFAPLLVLGTLDISWNRR----------FNE 194
            .|.|..:|.|:|:||.:|..|:|..|.|..:|...|..|..|..|   |.|.          ||
Mouse   109 RNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKEL---WLRNNPIESIPSYAFN- 169

  Fly   195 SGGDLYTGLGVNWKLSTL-RLDACSLNDL-HLPVNA-----PLKELSLRRNQLKRIPTQLPETLL 252
                         ::.:| |||...|..| ::...|     .|:.|:|....|:.||...|...|
Mouse   170 -------------RIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKL 221

  Fly   253 -RLDISDNLLEELLPEDTANLTQVRQLFIEDMPVLQRVVANSLTHVDVLETLSFQNSRQLSHLDA 316
             .||:|.|.|..:.|.....|..:::|:     ::|       :.:.|:|..:|.|.:.|..::
Mouse   222 DELDLSGNHLSAIRPGSFQGLMHLQKLW-----MIQ-------SQIQVIERNAFDNLQSLVEIN- 273

  Fly   317 EAFGPIMTTPTKKRALRSLSFRGTMLRTFNSTLAP--IFTQLAELD---LNGLPLQCDCELVWLK 376
                                     |...|.||.|  :||.|..|:   |:..|..|:|:::||.
Mouse   274 -------------------------LAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLS 313

  Fly   377 -----QLPVQTN--GRCYKPARIRGMLVTSARGDAFSC 407
                 ..|..|.  .||..|..::|..:.....:.|:|
Mouse   314 WWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTC 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4781	NP_611951.1	LRR	<90..367	CDD:443914	76/299 (25%)
		leucine-rich repeat	90..108	CDD:275380	4/17 (24%)
		leucine-rich repeat	109..132	CDD:275380	8/22 (36%)
		leucine-rich repeat	133..156	CDD:275380	10/22 (45%)
		leucine-rich repeat	157..180	CDD:275380	8/22 (36%)
		leucine-rich repeat	181..208	CDD:275380	6/36 (17%)
		leucine-rich repeat	230..253	CDD:275380	8/23 (35%)
		leucine-rich repeat	254..274	CDD:275380	7/19 (37%)
		leucine-rich repeat	275..299	CDD:275380	2/23 (9%)
		leucine-rich repeat	300..319	CDD:275380	4/18 (22%)
Lrrc4c	NP_848840.3	LRRNT	47..80	CDD:214470	10/80 (13%)
		LRR	<76..325	CDD:443914	77/303 (25%)
		LRR 1	77..98		6/20 (30%)
		leucine-rich repeat	78..101	CDD:275380	8/22 (36%)
		LRR 2	101..122		8/20 (40%)
		leucine-rich repeat	102..125	CDD:275380	10/22 (45%)
		LRR 3	125..146		7/20 (35%)
		leucine-rich repeat	126..149	CDD:275380	8/22 (36%)
		LRR 4	149..170		6/37 (16%)
		leucine-rich repeat	150..173	CDD:275380	6/39 (15%)
		LRR 5	173..195		7/21 (33%)
		leucine-rich repeat	174..198	CDD:275380	7/23 (30%)
		LRR 6	198..219		7/20 (35%)
		leucine-rich repeat	199..220	CDD:275380	7/20 (35%)
		LRR 7	220..241		7/20 (35%)
		leucine-rich repeat	221..244	CDD:275380	8/22 (36%)
		LRR 8	244..265		5/32 (16%)
		leucine-rich repeat	245..268	CDD:275380	6/34 (18%)
		LRR 9	268..289		7/46 (15%)
		leucine-rich repeat	269..290	CDD:275380	8/46 (17%)
		IG_like	360..443	CDD:214653
		Ig strand B	371..375	CDD:409390
		Ig strand C	383..387	CDD:409390
		Ig strand E	409..413	CDD:409390
		Ig strand F	423..428	CDD:409390
		Ig strand G	436..439	CDD:409390
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	463..482