DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3640 and Crispld2

DIOPT Version :9

Sequence 1:	NP_611950.1	Gene:	CG3640 / 37942	FlyBaseID:	FBgn0035042	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001297564.1	Gene:	Crispld2 / 78892	MGIID:	1926142	Length:	495	Species:	Mus musculus

Alignment Length:	243	Identity:	51/243 - (20%)
Similarity:	92/243 - (37%)	Gaps:	75/243 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 REARLIPLSNQLQAFIVHQVNFYRNQVASGGLSAFGPARRMASVRWDPELAQLAELAAKRCSLSG 117
            |..|.||:|::.:..::|  |..|.||       :.||..|..:.||.||.:.|...|.||
Mouse    46 RVRRAIPMSDRQEILMLH--NKLRGQV-------YPPASNMEHMTWDEELERSAAAWAHRC---- 97

  Fly   118 DGCRNTRRFKHVGQLTGH----VIFSAGKHSDLELLRHK-----ISNWFGQYMRASKDLQAADP- 172
                          |..|    ::.|.|::..:...|::     :.:|:.:.    ||.....|
Mouse    98 --------------LWEHGPAGLLRSIGQNLAVHWGRYRSPGFHVQSWYDEV----KDYTYPYPH 144

  Fly   173 -----------SSNISSFRQLIQESSTHMGCGVLRQRSHMLW-----HQQFIVCNFA-RRNMPRE 220
                       ....:.:.|::..::..:||.|...|:..:|     :..::|||:: :.|...|
Mouse   145 ECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGE 209

  Fly   221 QVYQVGVAATGCRSGRNPRY-----PNLCALQEEYDVNAVDRFHSKRP 263
            ..|:.|...:.|.|.    |     .|||        :..::.|..:|
Mouse   210 APYKHGRPCSECPSS----YGGGCLNNLC--------HRAEKPHKHKP 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3640	NP_611950.1	SCP_euk	65..213	CDD:240180	34/173 (20%)
Crispld2	NP_001297564.1	CAP	56..201	CDD:381818	34/175 (19%)
		LCCL	284..368	CDD:128866
		LCCL	387..486	CDD:367672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841299
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750