DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3640 and vap-2

DIOPT Version :9

Sequence 1:	NP_611950.1	Gene:	CG3640 / 37942	FlyBaseID:	FBgn0035042	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	206	Identity:	37/206 - (17%)
Similarity:	80/206 - (38%)	Gaps:	44/206 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NNNGTFGLDCGREARLIPLSNQLQAFIVHQVNFYRNQVA-----SGGLSAFGP-ARRMASVRWDP 100
            ::.|:|..|...      :|:..:.|.:.|.||||:::|     :|..:...| |.:|..:.:|.
Worm   299 DDGGSFQCDNSL------VSDVTRNFTLEQHNFYRSRLAKGFEWNGETNTSQPKASQMIKMEYDC 357

  Fly   101 ELAQLAELAAKRCSLSGDGCRNTRRFKHVGQLTGHVIFSAGKHSDLELLRHKISNWFGQYMRASK 165
            .|.:.|:..|..|..:     ::..::...|.....:.|........|:...:..|:       :
Worm   358 MLERFAQNWANNCVFA-----HSAHYERPNQGQNLYMSSFSNPDPRSLIHTAVEKWW-------Q 410

  Fly   166 DLQA-ADPSSN-------------ISSFRQLIQESSTHMGCGVLRQRSHMLWHQQFIVCNFA-RR 215
            :|:. ..|..|             |..:.|:..:.:..:|||:.....     ..::||::. ..
Worm   411 ELEEFGTPIDNVLTPELWDLKGKAIGHYTQMAWDRTYRLGCGIANCPK-----MSYVVCHYGPAG 470

  Fly   216 NMPREQVYQVG 226
            |....::|::|
Worm   471 NRKNNKIYEIG 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3640	NP_611950.1	SCP_euk	65..213	CDD:240180	30/167 (18%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	30/169 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820