DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3640 and crispld2

DIOPT Version :9

Sequence 1:	NP_611950.1	Gene:	CG3640 / 37942	FlyBaseID:	FBgn0035042	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_003199065.1	Gene:	crispld2 / 100535149	ZFINID:	ZDB-GENE-130131-1	Length:	508	Species:	Danio rerio

Alignment Length:	290	Identity:	62/290 - (21%)
Similarity:	107/290 - (36%)	Gaps:	88/290 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 REARLIPLSNQLQAFIVHQVNFYRNQVASGGLSAFGPARRMASVRWDPELAQLAELAAKRCSLSG 117
            |..|.|..|::.:...:|  |..|.:|       :..|..|..:.||.||.:.|...|::|
Zfish    51 RTRRAIEWSDREEILKLH--NKLRGEV-------YPTASNMEYMIWDDELERSATSWAEQC---- 102

  Fly   118 DGCRNTRRFKHVGQLTGHVIFSAGKHSDLELLRHK-----ISNWFGQYMRASKDLQAADP----- 172
                   :::|..|   .::.|.|::..:...|::     :..|:.:.    ||.....|
Zfish   103 -------QWEHGPQ---DLLMSIGQNLAVHWGRYRSPAYHVQAWYDEV----KDYTYPYPHECNP 153

  Fly   173 -------SSNISSFRQLIQESSTHMGCGVLRQRSHM---------LWHQQ-FIVCNFA-RRNMPR 219
                   ....:.:.||:..::..:||.|     |:         :|... ::|||:: :.|...
Zfish   154 WCPERCSGPMCTHYTQLVWATTNRVGCAV-----HVCPRMNVWGEIWENAVYLVCNYSPKGNWIG 213

  Fly   220 EQVYQVGVAATGCRSGRNPRY-----PNLC-----ALQEEYDVNAVDRFHSKRPLRIRF-----K 269
            |..||.|...:.|    .|.|     .|||     ..||..::|.|::  .:.||:.|.     :
Zfish   214 EAPYQHGRPCSQC----PPSYGGVCRDNLCYKRDSERQETPEMNEVEK--PQEPLQPRTTPPKPQ 272

  Fly   270 YSASHPSKVLGA-------DRDVAFHPNIK 292
            ...|.|.|...|       .|:.....|||
Zfish   273 PKPSSPKKPANAKPSSPKTTRNTYLAQNIK 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3640	NP_611950.1	SCP_euk	65..213	CDD:240180	32/174 (18%)
crispld2	XP_003199065.1	SCP_euk	61..206	CDD:240180	32/176 (18%)
		LCCL	299..382	CDD:128866	3/4 (75%)
		LCCL	402..495	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585817
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750