Protein Alignment Cyp9c1 and ERG11

DIOPT Version :9

• Sequence 1: NP_523850.1
• Gene: Cyp9c1 / 37941
• FlyBaseID: FBgn0015040
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 572
• Identity: 122/572 - (21%)
• Similarity: 196/572 - (34%)
• Gaps: 171/572 - (29%)

  Fly    39 IPLLGNIPWSVLMGKESYIKHSIDLHLRLKQHKVYGVFNLRDPLYYLSDPELIRQV--GIKNFDT 101
            ||.:.||.|.:|                      |.:...|.||.:...|.:...|  |:|.::.
Yeast    37 IPFIYNIVWQLL----------------------YSLRKDRPPLVFYWIPWVGSAVVYGMKPYEF 79

  Fly   102 FTNHRKGITEGFNDTSVISKSLL-------------------SLRDRRWKQMRSTL-TPTFTSLK 146
            |...:|    .:.|  :.|..||                   .|.|...:...:.| ||.|..
Yeast    80 FEECQK----KYGD--IFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGK-- 136

  Fly   147 IRQMFELIHFCN----VEAVDFVQRQLDAGTSELELKDFFTRYTNDVIATAAFGIQVNSFKDPNN 207
                 .:|:.|.    :|...||:..|        .|:.|..|. .:||...:    ..|:|..|
Yeast   137 -----GVIYDCPNSRLMEQKKFVKGAL--------TKEAFKSYV-PLIAEEVY----KYFRDSKN 183

  Fly   208 EFFSIGQRISEFTFWGGLKVML-----------YILMPKLMKAL--------------------- 240
              |.:.:|.:     |.:.||:           ..|:.|.|:|.
Yeast   184 --FRLNERTT-----GTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINF 241

  Fly   241 ---RVPVMDMNNVDYFKKLVFGA-----MKYRKEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAA 297
               .:|:......|:.:|.:.|.     .:.||...|...|:|..||              :::.
Yeast   242 VFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLM--------------KNST 292

  Fly   298 QQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEKPLD 362
            .:|..:..|.::....:.....|..|.|...::....|...|:||::|..|.:.|.:. |:|.|.
Yeast   293 YKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDG-GKKELT 356

  Fly   363 YDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVHINVGALHHDP 427
            ||.|..|..||..:.|:||...|...:.|....|..:.:....:.....    |.::.|..|...
Yeast   357 YDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYH----VLVSPGYTHLRD 417

  Fly   428 DNFPEPEQFRPERF--DEEHKHEIRQ--------------FTYLPFGVGQRSCIGNRLALMEVKS 476
            :.||...||...|:  |....:.:.:              ..|||||.|:..|||...|..::..
Yeast   418 EYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGV 482

  Fly   477 L--IFQLVLRYHLKPTDRT--PADMMSSI---SGFRLLPRELFWCKLESRGP 521
            |  ||...|::|. |..:|  |.|..|.:   :|    |.::.|   |.|.|
Yeast   483 LMSIFIRTLKWHY-PEGKTVPPPDFTSMVTLPTG----PAKIIW---EKRNP 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	118/563 (21%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	103/494 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050