DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9c1 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_523850.1	Gene:	Cyp9c1 / 37941	FlyBaseID:	FBgn0015040	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	133/535 - (24%)
Similarity:	231/535 - (43%)	Gaps:	97/535 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VFVELSIFVAFIGLLLYKWSVYTFGY---------FSKRGVAHEKPIPLLGNIPWSVLMGKESYI 57
            |...|.:.||.:  :|:.|.:..:.:         ..::|:......||:|:|..:|.|..|:..
plant     5 VVAALPVLVAVV--VLWTWRIVKWVWIKPKMLESSLKRQGLTGTPYTPLVGDIKRNVDMMMEARS 67

  Fly    58 K----------HSIDLHLR-LKQH-KVYGVFNLRDPLYYLSDPELIRQVGIKNFDTFTNHRKGIT 110
            |          ..:.|.|: |..| |.:.::....|...:::||.|::|    |:...:..|..|
plant    68 KPINVTDDITPRLLPLALKMLNSHGKTFFIWIGPLPTIVITNPEQIKEV----FNKVNDFEKAST 128

  Fly   111 EGFNDTSVISKSLLSLRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQLDAGTSE 175
              |....:::..|.|.:..:|...|..:.|.|...||:.|....:.|..|.|...::......|.
plant   129 --FPLIRLLAGGLASYKGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWEKLFTDKESP 191

  Fly   176 LELK--DFFTRYTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISEFTFWGGLKVML-------YI 231
            ||:.  .:....|.|||:..|||   :|:|:        ||||  |...|.|..::       ||
plant   192 LEVDVWPWLVNMTADVISHTAFG---SSYKE--------GQRI--FQLQGELAELIAQAFKKSYI 243

  Fly   232 ----LMP----KLMKALRVPVMDMNNVD-YFKKLVFGAMKYRKEQSIVRPDMIHLLMEAQRQFKA 287
                ..|    :.|||:.      ..|| ..:.:|....|.|:.......|::.:|:|:..:
plant   244 PGSRFYPTKSNRRMKAID------REVDVILRGIVSKREKAREAGEPANDDLLGILLESNSE--- 299

  Fly   288 EQEGSAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAV 352
            |.:|:..|.          :|::.:|.||:.||.||.:..|.:|...|..:.:.|.:...|::.|
plant   300 ESQGNGMSV----------EDVMKECKLFYFAGQETTSVLLVWTMVLLSHHQDWQARAREEVMQV 354

  Fly   353 KEQLGE--KPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDL 415
               |||  || |.::|..:|.:..:.:|.||.:||...:.|:...:.:|    ||  :.|.....
plant   355 ---LGENNKP-DMESLNNLKVMTMIFNEVLRLYPPVAQLKRVVNKEMKL----GE--LTLPAGIQ 409

  Fly   416 VHINVGALHHDPDNF-PEPEQFRPERF-DEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLI 478
            :::....:..|.:.: .:...|:|||| |...|....|.::.|||.|.|.|||...|::|.| :.
plant   410 IYLPTILVQRDTELWGDDAADFKPERFRDGLSKATKNQVSFFPFGWGPRICIGQNFAMLEAK-MA 473

  Fly   479 FQLVLR---YHLKPT 490
            ..|:|:   :.|.|:
plant   474 MALILQKFSFELSPS 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	126/491 (26%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	128/517 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810