DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9c1 and CYP709B2

DIOPT Version :9

Sequence 1:	NP_523850.1	Gene:	Cyp9c1 / 37941	FlyBaseID:	FBgn0015040	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_182218.2	Gene:	CYP709B2 / 819309	AraportID:	AT2G46950	Length:	572	Species:	Arabidopsis thaliana

Alignment Length:	513	Identity:	120/513 - (23%)
Similarity:	221/513 - (43%)	Gaps:	92/513 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 FSKRGVAHEKPIPLLGNIPWSVLMGKESYI----KHSIDLHLRLKQH-----KVYGVFNL----R 79
            |.|:|::..|...|.||:.....|..|:.:    .:|.|:..|:..|     ..||...|    .
plant    95 FKKQGISGPKYRILYGNLREIRKMKNEAKLMVLDPNSNDIVPRVLPHLQQWKSQYGETFLYWQGT 159

  Fly    80 DPLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKS---LLSLRDRRWKQMRSTLTPT 141
            ||...:||.||.:|:....|..|:..:       ....::..|   |:.:....|.:.|..|.|.
plant   160 DPRLCISDHELAKQILSNKFVFFSKSK-------TKPEILKLSGNGLIFVNGLDWVRHRRILNPA 217

  Fly   142 FTSLKIRQMFELIHFCNVEAVDFVQRQLDAGTSELE----LKDFFTRYTNDVIATAAFGIQVNSF 202
            |:..|::.|.:|:..|....  |::.:......|.|    :...|.|.|.|:|||||||   :|:
plant   218 FSMDKLKLMTQLMVDCTFRM--FLEWKKQRNGVETEQFVLISREFKRLTADIIATAAFG---SSY 277

  Fly   203 KDPNNEFFS-------IGQRISEFTFWGGLKVMLYILMPKLMKALRVPVMDMNNVDYFKKLVFGA 260
            .:....|.|       ....:::..|.|    :.|:..|   ..|::..:||......|:::  .
plant   278 AEGIEVFKSQLELQKCCAAALTDLYFPG----IQYLPTP---SNLQIWKLDMKVNSSIKRII--D 333

  Fly   261 MKYRKEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVA 325
            .:...|......|::.:::.|             :::.:.:.:.:.|:::.:|..||.||.||.|
plant   334 ARLTSESKDYGNDLLGIMLTA-------------ASSNESEKKMSIDEIIEECKTFFFAGHETTA 385

  Fly   326 TCLSFTSYELMMNPEVQEKLLAEILAVKEQLG-EKPLDYDTLMGMKYLNCVVSESLRKWPPAFIV 389
            ..|::::..|.::.:.||||..|:.   .:.| :|..|.:|...:|.:|.|..||||.:.|...:
plant   386 NLLTWSTMLLSLHQDWQEKLREEVF---NECGKDKIPDAETCSKLKLMNTVFMESLRLYGPVLNL 447

  Fly   390 DRMCGSDFQLKDEE---GEVVVNLREDDLVHINVGALHHDPDNF-PEPEQFRPERFDE------E 444
            .|:...|.:|.:.|   |..::         :.:..:|.|...: .:.::|.|.||..      .
plant   448 LRLASEDMKLGNLEIPKGTTII---------LPIAKMHRDKAVWGSDADKFNPMRFANGLSRAAN 503

  Fly   445 HKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQLVLRYHLKPT---DRTPADMMS 499
            |.:.:     |.|.:|.|:|||...|:||.|:::..::.|:.|..:   ...|||.::
plant   504 HPNAL-----LAFSMGPRACIGQNFAIMEAKTVLAMILQRFRLNLSADYKHAPADHLT 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	117/504 (23%)
CYP709B2	NP_182218.2	p450	89..571	CDD:299894	120/513 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810