DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9c1 and CYP711A1

DIOPT Version :9

Sequence 1:	NP_523850.1	Gene:	Cyp9c1 / 37941	FlyBaseID:	FBgn0015040	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_565617.2	Gene:	CYP711A1 / 817157	AraportID:	AT2G26170	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	140/526 - (26%)
Similarity:	229/526 - (43%)	Gaps:	100/526 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFVELSIFVAFIGLLLYKWSVYTFGYFSKRGVAHEKPIPLLGNIPWSVLMGKESYIKHSIDLHL 65
            :.|:..:..|..|.|....|||.        .|.....:||:|::|   ||.     |:..|:..
plant    22 IAFLTFAAVVIVIYLYRPSWSVC--------NVPGPTAMPLVGHLP---LMA-----KYGPDVFS 70

  Fly    66 RLKQHKVYG-VFNL---RDPLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKSLLSL 126
            .|.  |.|| :|..   |.||..:::.||.|:||||.|....|  :.|....:.:.:..|.|...
plant    71 VLA--KQYGPIFRFQMGRQPLIIIAEAELCREVGIKKFKDLPN--RSIPSPISASPLHKKGLFFT 131

  Fly   127 RDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQLDAGTSELELKDFFTRYTNDVIA 191
            ||:||.:||:|:...:....:..:...:|    ..:......||:...::...:.|.:.|.|:|.
plant   132 RDKRWSKMRNTILSLYQPSHLTSLIPTMH----SFITSATHNLDSKPRDIVFSNLFLKLTTDIIG 192

  Fly   192 TAAFGIQVN-SFKDP----------NNEFFSIGQRISEFTFWGGLKVMLYILMPKLMKALRVPVM 245
            .||||:... |.|.|          |...:|..|...:.:  |.|.::|.:|:|.|.:..|..:
plant   193 QAAFGVDFGLSGKKPIKDVEVTDFINQHVYSTTQLKMDLS--GSLSIILGLLIPILQEPFRQVL- 254

  Fly   246 DMNNVDYFKKLVFGAMKYRKEQSIVR--------------------PDMIHLLMEAQRQFKAEQE 290
                     |.:.|.|.:|.|::..|                    .|.:.|:::|:     |.:
plant   255 ---------KRIPGTMDWRVEKTNARLSGQLNEIVSKRAKEAETDSKDFLSLILKAR-----ESD 305

  Fly   291 GSAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQ 355
            ..|::.       |..|.:.|.......||..|.|..||...|.:..:.:|:::||.||    :.
plant   306 PFAKNI-------FTSDYISAVTYEHLLAGSATTAFTLSSVLYLVSGHLDVEKRLLQEI----DG 359

  Fly   356 LGEK---PLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVH 417
            .|.:   |..:|......||:.|:.|::|.:..:.:|.|....:.::    |..:  |.:...|.
plant   360 FGNRDLIPTAHDLQHKFPYLDQVIKEAMRFYMVSPLVARETAKEVEI----GGYL--LPKGTWVW 418

  Fly   418 INVGALHHDPDNFPEPEQFRPERFD---EEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIF 479
            :.:|.|..||.||||||:|:|||||   ||.||. ..:.::|||:|.|:|:|.|.||.|:|..:.
plant   419 LALGVLAKDPKNFPEPEKFKPERFDPNGEEEKHR-HPYAFIPFGIGPRACVGQRFALQEIKLTLL 482

  Fly   480 QLVLRY 485
            .|...|
plant   483 HLYRNY 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	132/490 (27%)
CYP711A1	NP_565617.2	cytochrome_P450	75..515	CDD:425388	122/455 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D786853at2759
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770