Protein Alignment Cyp9c1 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_523850.1
• Gene: Cyp9c1 / 37941
• FlyBaseID: FBgn0015040
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 159/529 - (30%)
• Similarity: 283/529 - (53%)
• Gaps: 61/529 - (11%)

  Fly     4 VELSIFVAFIGLLLYKWSVYTFGYFSKRGVAHEKPIPLLGNIPWSVLMGKESYIK--HSIDLHLR 66
            :|..:.:|.|.:|.|::...|.|.|.|:|:...||:|.||.:        .:|.:  ...|:...
  Rat     9 LETWLLLAIILVLFYRFGTRTHGIFKKQGIPGPKPLPFLGTV--------LNYYRGLWKFDMECY 65

  Fly    67 LKQHKVYGVFNLRDPLYYLSDPELIRQVGIKN-FDTFTNHRKGITEGFNDTSVISKSLLSLRDRR 130
            .|..|::|:|:.:.|::.:.|.|:|:.|.:|. |..|||.|     ......::|||:...:|..
  Rat    66 KKCGKIWGLFDGQTPVFAIMDTEMIKSVLVKECFSVFTNRR-----NIGPVGIMSKSISVAKDEE 125

  Fly   131 WKQMRSTLTPTFTSLKIRQMFELI-HFCNVEAVDFVQRQLDAGTSELELKDFFTRYTNDVIATAA 194
            ||:.|:.|:|||||.::::||.:| |:.:: .|.:::::::.| ..|.:|:.|..|:.|||.:.:
  Rat   126 WKRYRAFLSPTFTSGRLKEMFPIIEHYGDI-LVKYLKQKVEKG-KPLAMKEVFGAYSMDVITSTS 188

  Fly   195 FGIQVNSFKDPNNEFFSIGQRISEFTFWGG--LKVMLYILMPKLMKALRVPVMDMNNVDYFKKLV 257
            |.:.:||..:|.:.|....::...|.|:..  |.|:|:..:..:.:.|.:.:...::|.:|:|.|
  Rat   189 FEVNINSINNPKDPFVEKVKKFQRFDFFDPLFLSVVLFPFLTPIYEMLNICLFPKDSVAFFQKFV 253

  Fly   258 FGAMKYRKEQSIV------RPDMIHLLMEAQRQFKAEQEGSAESAAQQDKAEFNDDDLLAQCLLF 316
                 ||.:|:.:      |.|.:.|:|.|....|.:....|          .:|.:::||.::|
  Rat   254 -----YRMKQTRLDSKHKHRVDFLQLMMNAHNNSKDKVSHKA----------LSDIEIVAQAIIF 303

  Fly   317 FSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEK-PLDYDTLMGMKYLNCVVSESL 380
            ..|.:||.::.|||..|.|..:|:.|:||..||   ...|..| |..|||:|.|:||:.|::|:.
  Rat   304 IFASYETTSSTLSFVLYSLATHPDSQKKLQEEI---DRALPNKAPPTYDTVMEMEYLDMVLNETP 365

  Fly   381 RKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVHINVGALHHDPDNFPEPEQFRPERFDEEH 445
            |.:|..:.::|:|..|.:|   :|   |.:.:..:|.|....|.|||.::||||:|.||||.:|:
  Rat   366 RLYPIGYRLERVCKKDIKL---DG---VFIPKGSVVMIPFYTLQHDPQHWPEPEEFLPERFSKEN 424

  Fly   446 KHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQLVLRYHLKPTDRTPADMMSS---ISG---- 503
            |..|..:.|||||.|.|:|||.|.|||.:|..:.:::..:..:..:.|...:..|   :.|
  Rat   425 KGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLCEETQIPLKLSRQRLFGPEKP 489

  Fly   504 --FRLLPRE 510
              .:::||:
  Rat   490 IVLKVVPRD 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	CYP6-like	68..513	CDD:410679	142/463 (31%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	140/456 (31%)