DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9c1 and Cyp6d5

DIOPT Version :9

Sequence 1:	NP_523850.1	Gene:	Cyp9c1 / 37941	FlyBaseID:	FBgn0015040	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_650327.1	Gene:	Cyp6d5 / 41706	FlyBaseID:	FBgn0038194	Length:	508	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	162/504 - (32%)
Similarity:	265/504 - (52%)	Gaps:	29/504 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLYKWSVYTFGYFSKRGVAHEKPIPLLG-NIPW----SVLMGKESYIKHSIDLHLRLKQHKVYGV 75
            |||.:..:||.|:.::|      .|..| :||:    ||..||.|:.....|::...|: .|.|:
  Fly    13 LLYVYLKWTFSYWDRKG------FPSTGVSIPFGALESVTKGKRSFGMAIYDMYKSTKE-PVIGL 70

  Fly    76 FNLRDPLYYLSDPELIRQVGIKNFDTFTNHRKGI-TEGFNDTSVISKSLLSLRDRRWKQMRSTLT 139
            :....|...:.|.:|...|.:|:|.:|  |.:|: .:..||.  :|.||..:....|:.:|:.||
  Fly    71 YLTLRPALLVRDAQLAHDVLVKDFASF--HDRGVYVDEKNDP--MSASLFQMEGASWRALRNKLT 131

  Fly   140 PTFTSLKIRQMFELIHFCNVEAVDFVQRQLDA-GTSELELKDFFTRYTNDVIATAAFGIQVNSFK 203
            |:|||.|::.|||.......:.||.:::||.| |..|||||.....|..|:|||..||:.|:||.
  Fly   132 PSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDVDSFA 196

  Fly   204 DPNNEFFSIGQRISEFTFWGGLKVMLYILMPKLMKALRVPVMDMNNVDYFKKLVFGAMKYRKEQS 268
            ||||||..|.::::.......::.....|.|.|.|............:..::|....:..|::.:
  Fly   197 DPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGWKQEATERMRELSNRTVDLREQNN 261

  Fly   269 IVRPDMIHLLMEAQRQFKAEQEG---SAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSF 330
            |||.|::.||::.:.|.|...:.   ||||.....|: .:.|.:..|..||:.||:||.|:..||
  Fly   262 IVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKS-MSKDLIAGQLFLFYVAGYETTASTTSF 325

  Fly   331 TSYELMMNPEVQEKLLAEILAVKEQLGEKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGS 395
            |.|||..||||.||...::.:..|:.|.| |.||.:..||||...:.|:.||:|...:::|:|..
  Fly   326 TLYELTQNPEVMEKAKEDVRSAIEKHGGK-LTYDAISDMKYLEACILETARKYPALPLLNRICTK 389

  Fly   396 DFQLKDEEGEVVVNLREDDLVHINVGALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVG 460
            |:.:.|.:    :.:::...:.|::..:|.|.:.||:|..::|||:.|..| :..|..|||||.|
  Fly   390 DYPVPDSK----LVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERYLENGK-DYTQAAYLPFGEG 449

  Fly   461 QRSCIGNRLALMEVKSLIFQLVLRYHLKPTDRTPADMMSSISGFRLLPR 509
            .|.|||.|:..:.||..|.:::..:.|: ..:...::...:.|..|:|:
  Fly   450 PRMCIGARMGKVNVKIAIAKVLSNFDLE-IRKEKCEIEFGVYGIPLMPK 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	155/483 (32%)
Cyp6d5	NP_650327.1	p450	66..478	CDD:278495	141/423 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461141
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I1773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900