DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9c1 and cyp-25A6

DIOPT Version :9

Sequence 1:	NP_523850.1	Gene:	Cyp9c1 / 37941	FlyBaseID:	FBgn0015040	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001360017.1	Gene:	cyp-25A6 / 187059	WormBaseID:	WBGene00019438	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	225	Identity:	60/225 - (26%)
Similarity:	102/225 - (45%)	Gaps:	28/225 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFVEL-SIFVAFIGLLLYKWSV--YTFGYFSKRGVAHEKPIPLLGNIPWSVLMGKESYIKHSID 62
            |.|:.| ||.|:.:..::|....  ..|....|.|::..:|..|:||:...:....:.....|.|
Worm     1 MAFLILTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSYD 65

  Fly    63 LHLRLKQHKVYG-VFNLRDPLYY-------LSDPELIRQVGIKNFDTFTNHR-KGITEGFNDTSV 118
            .:.:|  ||.:| .|.    :|:       :::.|.|::|.||||..|::.. ..|.|   |..:
Worm    66 WYNKL--HKQFGETFG----IYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIE---DNKL 121

  Fly   119 ISKSLLSLRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDF---VQRQLDAGTSELELKD 180
            ....|.:..:..||..||.:.|.|::.|::.|.|.||    ..||.   :.::..:...:.::.|
Worm   122 KESLLQNTYESGWKHTRSAIAPIFSTGKMKAMHETIH----SKVDLFLEILKEKASSGQKWDIYD 182

  Fly   181 FFTRYTNDVIATAAFGIQVNSFKDPNNEFF 210
            .|...|.|||...||.|..|..:|.|:.|:
Worm   183 DFQGLTLDVIGKCAFAIDSNCQRDRNDIFY 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	50/186 (27%)
cyp-25A6	NP_001360017.1	p450	37..>215	CDD:386267	50/189 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650