Protein Alignment Cyp9c1 and CYP4F22

DIOPT Version :9

• Sequence 1: NP_523850.1
• Gene: Cyp9c1 / 37941
• FlyBaseID: FBgn0015040
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 96/438 - (21%)
• Similarity: 189/438 - (43%)
• Gaps: 83/438 - (18%)

  Fly   119 ISKSLLSLRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQ---RQLDAGTS-ELELK 179
            :...||..:..:|.:.|..|||.|....::...::.:    ::.|.:.   |.|..|:: .|::.
Human   140 LGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN----QSADIMHAKWRHLAEGSAVSLDMF 200

  Fly   180 DFFTRYTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISEFTFWGGLKVMLYILMPKLMKALRVPV 244
            :..:..|.|.:....|....|           ..:::|::             :..:::...:.|
Human   201 EHISLMTLDSLQKCVFSYNSN-----------CQEKMSDY-------------ISAIIELSALSV 241

  Fly   245 MDMNNVDYFKKLVF--GAMKYRKEQSIVRPDMIH-----LLMEAQRQFKAEQEGSAES------- 295
            .....:.::...::  .|...|..|:.   ||:|     ::.|.:|..:  |:| ||:
Human   242 RRQYRLHHYLDFIYYRSADGRRFRQAC---DMVHHFTTEVIQERRRALR--QQG-AEAWLKAKQG 300

  Fly   296 -----------AAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEI 349
                       |..:|..|.:|:|:.|:...|...|.:|.::.:|:..:.|...||.|||...||
Human   301 KTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEI 365

  Fly   350 LAVKEQLGEKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDD 414
            ..|.:....:.|::|.|..:.:....:.||||::||..:|.|.|..|.:|.|  |.::   .:..
Human   366 QEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPD--GRII---PKGI 425

  Fly   415 LVHINVGALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIF 479
            :..:::...||:|..:|:.:.:.|.|||.::..:.....|:||..|.|:|||...|:.|::.::.
Human   426 ICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVA 490

  Fly   480 QLVLRYHLKPTDRT------PADMMSSISGFRLLPRELFWCKLESRGP 521
            ..:||:.|. .|||      |..::.:.:|        .|.|:|...|
Human   491 LTLLRFRLS-VDRTRKVRRKPELILRTENG--------LWLKVEPLPP 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	92/429 (21%)
CYP4F22	NP_775754.2	p450	60..524	CDD:278495	93/431 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900