DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cyp9c1 and Cyp4a32

DIOPT Version :9

Sequence 1:NP_523850.1 Gene:Cyp9c1 / 37941 FlyBaseID:FBgn0015040 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_001093651.1 Gene:Cyp4a32 / 100040843 MGIID:3717148 Length:509 Species:Mus musculus


Alignment Length:435 Identity:107/435 - (24%)
Similarity:177/435 - (40%) Gaps:94/435 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 ISKSLLSLRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQLD-----AG-TSELE 177
            |...||.|..:.|.|.|..|||.|       .::::........|.::..||     || .|.:|
Mouse   126 IGYGLLLLNGQPWFQHRRMLTPAF-------HYDILKPYVKNMADSIRLMLDKWERLAGQDSSIE 183

  Fly   178 LKDFFTRYTNDVIATAAF----GIQVN-SFK-------DPNNEFFSIGQRISEFTFWGGLKVMLY 230
            :....:..|.|.:...||    .:||: ::|       |.||.|.|..:.|..      ....:|
Mouse   184 IFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFH------QNDTIY 242

  Fly   231 ILMPKLMKALRVPVMDMNNVDYFKKLVFGAMKYRKEQSIVRPDMIHLLMEAQRQFKAEQEGSAES 295
            .|......|.:...:..::.|       |.:|.||:|                   .:.||..|:
Mouse   243 RLSSNGRLAKQACQLAHDHTD-------GVIKMRKDQ-------------------LQDEGELEN 281

  Fly   296 AAQQDKAEF---------------NDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKL 345
            ..::.:.:|               :|.||.|:...|...|.:|.|:.:|:..|.|..:||.|::.
Mouse   282 IKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRC 346

  Fly   346 LAEILAVKEQLGE-KPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVN 409
            ..|   |:..||: ..:.:|.|..:.|....:.|:||.:||...:.|...:.....|..     :
Mouse   347 REE---VQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGR-----S 403

  Fly   410 LREDDLVHINVGALHHDPDNFPEPEQFRPERF---DEEHKHEIRQFTYLPFGVGQRSCIGNRLAL 471
            |.:...|.:::..|||:|..:|.||.|.|.||   ...|.|     ::|||..|.|:|||.:.|:
Mouse   404 LPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSH-----SFLPFSGGARNCIGKQFAM 463

  Fly   472 MEVKSLIFQLVLRYHLKP-TDRTPADM----MSSISGFRLLPREL 511
            .|:|.::...:|.:.|.| ..|.|..:    :.|.:|..|..::|
Mouse   464 SELKVIVALTLLHFELLPDPTRVPEPLARIVLKSKNGIYLHLKKL 508

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp9c1NP_523850.1 p450 37..514 CDD:299894 107/435 (25%)
Cyp4a32NP_001093651.1 p450 52..503 CDD:278495 105/428 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.