Protein Alignment Adck1 and ADCK2

DIOPT Version :9

• Sequence 1: NP_001286851.1
• Gene: Adck1 / 37938
• FlyBaseID: FBgn0035039
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_443085.2
• Gene: ADCK2 / 90956
• HGNCID: 19039
• Length: 626
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 120/570 - (21%)
• Similarity: 187/570 - (32%)
• Gaps: 203/570 - (35%)

  Fly     4 RRVLGYGVVGAGLASA--------GWSLHTNDYDPNSLGIVRL-SRSAAAVVD-------VALTY 52
            |||...|..|||.|.:        |..||           :|| .|:.|.:|.       ..|||
Human    68 RRVRCSGAAGAGPAESLPRAGPLGGVFLH-----------LRLWLRAGALLVKFFPLLLLYPLTY 121

  Fly    53 KRELYYKEWDKETPEYKAEKSRVHKIAAEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMK 117
            ........|             :|     .||:....:...|||:||.......|..:.|.....
Human   122 LAPSVSTLW-------------LH-----LLLKATETSGPTYIKLGQWASTRRDLFSEAFCAQFS 168

  Fly   118 VLHSDAPQNPIEDLYKVIRQDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGEL--------- 173
            .||.....:|.....:.:||....:...|.....|||:|:..:|||:||...|..|
Human   169 KLHVRVTPHPWTHTERFLRQAFGDDWGSILSFENREPVGSGCVAQVYKAYANTAFLETDSVQRLG 233

  Fly   174 ----------------------------------------------------------------- 173
                                                                             
Human   234 RASCLPPFSHTGAVGGLRELFGYLGNGRKPPENLADQSFLERLLLPKADLVGSNAGVSRAQVPGH 298

  Fly   174 ---------VAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPDFKIHWL-----VEESKKNLPIE 224
                     |||||.||.:.....:|:..|::...||. :.|..|  ||     |||.:|.:..:
Human   299 QPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRVLG-VLPGIK--WLSLPEIVEEFEKLMVQQ 360

  Fly   225 LDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVL---------VMEYLEGGHVTDLDYIRR 280
            :|...|.:|.|.....|:....::.|.....:.:..||         |..|.:.|...||    :
Human   361 IDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVPVSSYQQAGIPVDL----K 421

  Fly   281 NKIDSFAVANRIG-QLYSEMIFRTGFVHSDPHPGNILVR------------------------RT 320
            .||      .|:| .:..:|||...|||:|.|||||||:                        ..
Human   422 RKI------ARLGINMLLKMIFVDNFVHADLHPGNILVQGANGLSSSQEAQLQQADICDTLVVAV 480

  Fly   321 PEN--SLEIVLLDHGLYANLTDKFRYDYSNLWLSILKVDRKAMRQ---HSEQLGIKGDLYGLFAC 380
            |.:  .|.:||||.|:.|.|......::..::::::....:.:.:   |..:.....|:.|
Human   481 PSSLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAVVMGQGQRVAELILHHARASECRDVEG---- 541

  Fly   381 MVTGRPWETVMQGLTKVKYSKEEKNTLQNNTSLVLPHISDVLEQVDRQML 430
                  ::|.|..|.    ::..|||:    :|...|:|.:|..|.:.::
Human   542 ------FKTEMAMLV----TQARKNTI----TLEKLHVSSLLSSVFKLLM 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	77/377 (20%)
ADCK2	NP_443085.2	AarF	134..618	CDD:223733	99/475 (21%)
		ADCK2-like	169..553	CDD:270873	82/410 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2751
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.760