DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adck1 and ATH9

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_565923.1	Gene:	ATH9 / 818597	AraportID:	AT2G40090	Length:	538	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	188/504 - (37%)
Similarity:	296/504 - (58%)	Gaps:	36/504 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VVGAGL-ASAGWSLHTNDYDPN-SLGI-----VRLSRSAAAVVDVALTYKRELY-YKEWDKETPE 67
            |||..| ..:|.:...:..||: :|.:     |||.|:......:|..|:..|. ..|...|..:
plant    15 VVGTALCGGSGAAFIASSDDPSTTLKLCTSIPVRLYRNTVTAASIAFDYEYSLLGLAEGSSERAK 79

  Fly    68 YKAEKSRVHKIAAEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMK-VLHSDAPQNPIEDL 131
            .|.|   ||..:|:||.:|...|.|:|||:|||||.||||:|:|:|:||: .:.:..|.:..|.:
plant    80 VKHE---VHLRSAQKLQELCFKNGGIYIKLGQHIGQLEYLVPEEYVRTMRESMLNKCPISSYEQV 141

  Fly   132 YKVIRQDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMEL 196
            .:|.::::...|:::|..|:..|:.:|||||||.||...|:.|||||||.::...:..|...:.:
plant   142 CEVFKKEVGEMPDQVFAEFDPVPIASASLAQVHVARTHDGKKVAVKVQHAHMTDTAAADTAAVGV 206

  Fly   197 AVNVLARIFPDFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYS-----WLRVPKIYWKY 256
            .||.|.||||.|...||::|..::||.|||||.|.:|.||....|:|.|     ::..|.|||..
plant   207 LVNTLHRIFPSFDYRWLLDEMSESLPKELDFLVEAKNNEKCLDNFRKLSPHIAEYVYAPTIYWNL 271

  Fly   257 SSSRVLVMEYLEGGHVTDLDYIRRNKIDSFAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTP 321
            |:|::|.||:::|..|.|:|.||:..|..:.|:..:.|.::||:|:.||||.|||..|::||..|
plant   272 STSKLLTMEFMDGAQVNDVDKIRKLGIQPYEVSKLVSQTFAEMMFKHGFVHCDPHAANLIVRPDP 336

  Fly   322 --------ENSLEIVLLDHGLYANLTDKFRYDYSNLWLSILKVDRKAMRQHSEQLGIKGDLYGLF 378
                    :...::|:||||||..|....|::|::||.:::..|.||:::|||:||...|||.||
plant   337 SGKRNIYGKRKPQLVILDHGLYKELDFNTRFNYASLWKALVFSDAKAIKEHSEKLGAGDDLYVLF 401

  Fly   379 ACMVTGRPWETVMQGLTKVKY-----SKEEKNTLQNNTSLVLPHISDVLEQVDRQMLLILKTNDL 438
            |.::|.|||:.|:.  |.|.:     :||:.:.||...|.....||::|.::.|.:||:|||||.
plant   402 AGILTMRPWKQVID--TSVDHLVIQGNKEDVSELQMYASQYFSEISELLRRLPRVILLMLKTNDC 464

  Fly   439 IRGIESTLRTQNRMTAFWVMSKCCVQSSYAEQRAKQSDSGSSRILWLRV 487
            :|.:.:.|...:.:.:|.::.|.   ||.|...||:::. .|.:.||:|
plant   465 LRSVNNELMQGSSLESFLIIGKV---SSQAVLEAKRAEK-KSLMKWLKV 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	100/263 (38%)
ATH9	NP_565923.1	AarF	48..>393	CDD:223733	136/347 (39%)
ATH9	NP_565923.1	ADCK1-like	128..392	CDD:270871	100/263 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	165	1.000	Domainoid score	I1220
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6493
Inparanoid	1	1.050	313	1.000	Inparanoid score	I735
OMA	1	1.010	-	-		QHG57752
OrthoDB	1	1.010	-	-		D790106at2759
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	1	1.000	-	-		oto3404
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	1	1.100	-	-	LDO	PTHR43173
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3709
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840