DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adck1 and ATATH8

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_565900.1	Gene:	ATATH8 / 818504	AraportID:	AT2G39190	Length:	814	Species:	Arabidopsis thaliana

Alignment Length:	593	Identity:	135/593 - (22%)
Similarity:	231/593 - (38%)	Gaps:	148/593 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VGAGLASAG----------------WSLHTNDYDPNSL---GIVRLSRSAAAVVDVAL------- 50
            :|.||..|.                |..|..|:...:|   ...:.|.|....||:.:
plant    61 IGIGLRWANEAFRVPEVTKSAEELFWLRHLEDHTSQNLKSQSWPQPSYSGLTGVDLFMADVKALE 125

  Fly    51 TYKRELY--YKEWDKETPE-YKAE------KSRVHKI---------------------------- 78
            ||....|  .|.|.:..|| |.::      ..|.|.:
plant   126 TYAGYFYSLSKMWSRPLPEVYDSQAVADYFNCRPHVVAFRLLEVFSAFTIAAIRLRTSASVKGKS 190

  Fly    79 --AAEKLLQLI----CINKG-VYIKVGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLYKVIR 136
              |:|::..::    .::.| .:|||||.:.....::..|..:.:..||...|..|..:..|::.
plant   191 LEASEQIFGMVLKETMLHLGPTFIKVGQSLSTRPDIIGTEISKALSELHDRIPPFPWPEAVKILE 255

  Fly   137 QDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVL 201
            .:|....|..|..|.:|.:..||..||::.|...|..||||||.|.::.....|:..:.|.:.||
plant   256 GELGGPVESFFSQFSQETVAAASFGQVYRGRTLDGADVAVKVQRPDLRHAVLRDIYILRLGLGVL 320

  Fly   202 ARIFP---DFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVLV 263
            .::..   |.:::  .:|....|..||||..|..||.:..:...::|::||||:|...:..|||.
plant   321 RKVAKRENDIRVY--ADELGMGLAGELDFTLEAANASEFQEAHARFSYIRVPKVYQHLTRKRVLT 383

  Fly   264 MEYLEGGHVTDLDYI-------------------RRNKIDSFAVANRIGQLYSEMIFRTGFVHSD 309
            ||::.|...|||..|                   ||..:|   :.|:..:.....:..||.:|:|
plant   384 MEWMVGESPTDLLAISSGYSDHDNESHEKQKIEARRRLLD---LVNKGVEATLVQLLDTGILHAD 445

  Fly   310 PHPGNILVRRTPENSLEIVLLDHGLYANLTDKFRYDYSNLWLSILKVDRKAMRQHSEQLGIKGDL 374
            |||||:  |.|  .|.:|..||.||...:..|.:.   .:..||:.:             :.||
plant   446 PHPGNL--RYT--TSRQIGFLDFGLVCRMQRKHQL---AMLASIVHI-------------VNGD- 489

  Fly   375 YGLFACMVTGR-PWETVMQGLTKVKYSKEEKNTLQNNTSLV--LPHI--SDVLEQVDRQML---- 430
               :||:|... ..:.:..|:...:::.:.:..| ....|:  :|.|  :.||.::....|
plant   490 ---WACLVESLIDMDVITPGVNTRRFTLDLEYAL-GEVKLINGIPDIEFTKVLSKIVNVALKYQL 550

  Fly   431 -------LILKTNDLIRGI----ESTLRTQNRMTAFWVMSKCCVQSSYAEQRAKQSDSGSSRILW 484
                   |:|::...:.|:    :...:|......| |:.|...::|.|.::...     |.:|.
plant   551 RMPPYFTLVLRSLACLEGLAAAGDPNFKTFEAAYPF-VVQKLITENSAATRKILH-----SAVLN 609

  Fly   485 LRVRERWE 492
            .:...|||
plant   610 RKKEFRWE 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	77/272 (28%)
ATATH8	NP_565900.1	AarF	161..691	CDD:223733	113/493 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810