DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adck1 and Adck1

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_030102793.1	Gene:	Adck1 / 72113	MGIID:	1919363	Length:	535	Species:	Mus musculus

Alignment Length:	503	Identity:	239/503 - (47%)
Similarity:	337/503 - (66%)	Gaps:	26/503 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVLGYGVVGAGLASAGWSLHTNDYDPNSLGI-VRLSRSAAAVVDV-ALTYKRELYYKEWDKETPE 67
            |..|.||             |:.::|...|. .|.|.||.||:.. .||..|.:.|     .:.|
Mouse    30 RYTGTGV-------------TDGHEPQDAGNGTRFSASATAVISYDYLTSLRSVPY-----GSEE 76

  Fly    68 YKAEKSRVHKIAAEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLY 132
            |...:|:||..:|.:|.:|.|.|:|.:||||||:|||:||||:|:..|:|||||.|||:.::::.
Mouse    77 YLQRRSQVHLRSARRLFELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEVR 141

  Fly   133 KVIRQDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELA 197
            :|||:||.....::|.||:..|||.|||||||||.|..|..||||||||.|:..|..|:..||:.
Mouse   142 QVIREDLGKEIHDLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVL 206

  Fly   198 VNVLARIFPDFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVL 262
            |..:.::||||:..|||:|:|||||:|||||||||||||||...:.:.:|:||:|:|:.|:.|||
Mouse   207 VLAVKQLFPDFEFMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFDFLKVPQIHWELSTKRVL 271

  Fly   263 VMEYLEGGHVTDLDYIRRNKIDSFAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTPE-NSLE 326
            :||::|||.|.|..|:.:|:||...::..:|::||||||..||||.||||||:|||:.|: ...|
Mouse   272 LMEFVEGGQVNDRAYMEKNQIDVNEISCHLGKMYSEMIFVNGFVHCDPHPGNVLVRKRPDTGKAE 336

  Fly   327 IVLLDHGLYANLTDKFRYDYSNLWLSILKVDRKAMRQHSEQLGIKGDLYGLFACMVTGRPWETVM 391
            |||||||||..||::||.||.:||.|::..|...::|:|::|| ..|||.|||||:|.|.|::|.
Mouse   337 IVLLDHGLYQVLTEEFRLDYCHLWQSLIWTDMDGLKQYSQRLG-AADLYPLFACMLTARSWDSVK 400

  Fly   392 QGLTKVKYSKEEKNTLQNNTSLVLPHISDVLEQVDRQMLLILKTNDLIRGIESTLRTQNRMTAFW 456
            ||:.:...|..|.:.::||.:..||.||.:|..|.||||||||||||:|.||:||.|::..::|.
Mouse   401 QGIGQAPVSATEDSEIRNNAACYLPEISQLLNHVPRQMLLILKTNDLLRSIETTLGTRSSASSFL 465

  Fly   457 VMSKCCVQSSYAEQRAKQSDSGS-SRILWLRVRERWELFKLNCYYLYL 503
            .||:||:: :.||.  |:.|:|| .|...:...|.:.|:::|.:.|.|
Mouse   466 NMSRCCIR-ALAEH--KKRDAGSFFRRTQISFSEAFSLWQINLHELLL 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	134/251 (53%)
Adck1	XP_030102793.1	ADCK1-like	127..379	CDD:270871	141/252 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838076
Domainoid	1	1.000	231	1.000	Domainoid score	I2431
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6493
Inparanoid	1	1.050	460	1.000	Inparanoid score	I1552
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57752
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	1	1.000	-	-		oto94403
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	1	1.100	-	-	LDO	PTHR43173
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1843
SonicParanoid	1	1.000	-	-		X3709
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790