DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adck1 and Coq8a

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001156762.1	Gene:	Coq8a / 67426	MGIID:	1914676	Length:	645	Species:	Mus musculus

Alignment Length:	300	Identity:	74/300 - (24%)
Similarity:	144/300 - (48%)	Gaps:	26/300 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 AEKLLQLICINKGVYIKVGQHIGALE--YLLPKEFVQTMKVLHSDAPQNPIEDLYKVIRQDLHCN 142
            ||:::..:|..:|..:|:||.:...:  ::.| ...:..:.:...|...|::.:.|.:..||..:
Mouse   257 AERIVSTLCKVRGAALKLGQMLSIQDDAFINP-HLAKIFERVRQSADFMPLKQMTKTLNSDLGPH 320

  Fly   143 PEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPD 207
            ..:..:.||..|...||:.|||.||:|.|..||:|:|:|.|..:...|:..: :||..::.:.|:
Mouse   321 WRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNL-MAVLNMSNMLPE 384

  Fly   208 --FKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVLVMEYLEG- 269
              |..| |::..::.|.:|.|:..|...|:|..:..|.:.:..||:|..:..|..||..|.:.|
Mouse   385 GLFPEH-LIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELISGF 448

  Fly   270 --GHVTDLDYIRRNKIDSFAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTPENSLEIVLLDH 332
              .....|....||:|     ...|..|....:|....:.:||:..|...  .|:.. ::.|||.
Mouse   449 PLDQAEGLSQEVRNEI-----CYNILVLCLRELFEFHVMQTDPNWSNFFY--DPQQH-KVALLDF 505

  Fly   333 GLYANLTDKFRYDYSNLWLSILKV----DRKAMRQHSEQL 368
            |    .|.::...:::|::.:::.    ||:|:.:.|.::
Mouse   506 G----ATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEM 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	66/259 (25%)
Coq8a	NP_001156762.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	99..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..200
		KxGQ motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	273..276		1/2 (50%)
		ABC1_ADCK3	292..542	CDD:270872	66/263 (25%)
		AAAS motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	334..337		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810