Protein Alignment Adck1 and ADCK1

DIOPT Version :9

• Sequence 1: NP_001286851.1
• Gene: Adck1 / 37938
• FlyBaseID: FBgn0035039
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001353416.1
• Gene: ADCK1 / 57143
• HGNCID: 19038
• Length: 580
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 235/547 - (42%)
• Similarity: 340/547 - (62%)
• Gaps: 64/547 - (11%)

  Fly    16 LASAGWSLHTNDY-DPNSLGIVRLSRSAAAVVDVALTYKRELYYKEWDKETPEYKAEKSRVHKIA 79
            ||::|...::|.| |||..|.||:.|:.|....::..|...|....:..|  ||...:|:||..:
Human    16 LAASGIYFYSNKYLDPNDFGAVRVGRAVATTAVISYDYLTSLKSVPYGSE--EYLQLRSKVHLRS 78

  Fly    80 AEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLYKVIRQDLHCNPE 144
            |.:|.:|.|.|:|.:||||||:|||:||||:|:..|:|||||.|||:.::::.:|||:||.....
Human    79 ARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEIRQVIREDLGKEIH 143

  Fly   145 EIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPDFK 209
            ::|.||:..|||||||||||||.|..|..||||||||.|:..|..|:..||:.|..:.::||:|:
Human   144 DLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEVLVLAVKQLFPEFE 208

  Fly   210 IHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVLVMEYLEGGHVTD 274
            ..|||:|:|||||:||||||||||||||::..:.:.:|:||:|:|..|:.|||:||:::||.|.|
Human   209 FMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLLMEFVDGGQVND 273

  Fly   275 LDYIRRNKID------------------------------------------------------- 284
            .||:.|||||
Human   274 RDYMERNKIDVNEVRSRAQGCCAGERGLGQGCPGSACVSRSSEKVSHLLSANDFSSSYHVQALSA 338

  Fly   285 --SFAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTP-ENSLEIVLLDHGLYANLTDKFRYDY 346
              :..::..:|::||||||..||||.||||||:|||:.| ....||||||||||..||::||.:|
Human   339 LATIEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVLLDHGLYQMLTEEFRLNY 403

  Fly   347 SNLWLSILKVDRKAMRQHSEQLGIKGDLYGLFACMVTGRPWETVMQGLTKVKYSKEEKNTLQNNT 411
            .:||.|::..|.|.::::|::|| .||||.|||||:|.|.|::|.:|:::...:..|...::||.
Human   404 CHLWQSLIWTDMKRVKEYSQRLG-AGDLYPLFACMLTARSWDSVNRGISQAPVTATEDLEIRNNA 467

  Fly   412 SLVLPHISDVLEQVDRQMLLILKTNDLIRGIESTLRTQNRMTAFWVMSKCCVQSSYAEQRAKQSD 476
            :..||.||.:|..|.||||||||||||:||||:.|.|:...::|..||:||:: :.||.:.|.:.
Human   468 ANYLPQISHLLNHVPRQMLLILKTNDLLRGIEAALGTRASASSFLNMSRCCIR-ALAEHKKKNTC 531

  Fly   477 SGSSRILWLRVRERWELFKLNCYYLYL 503
            |...| ..:...|.:.|:::|.:.|.|
Human   532 SFFRR-TQISFSEAFNLWQINLHELIL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	134/308 (44%)
ADCK1	NP_001353416.1	ADCK1-like	117..426	CDD:270871	134/308 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147986
Domainoid	1	1.000	230	1.000	Domainoid score	I2470
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6493
Inparanoid	1	1.050	450	1.000	Inparanoid score	I1617
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57752
OrthoDB	1	1.010	-	-		D350846at33208
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	1	1.000	-	-		oto90819
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	1	1.100	-	-	LDO	PTHR43173
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1843
SonicParanoid	1	1.000	-	-		X3709
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800