DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adck1 and Adck1

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_038968578.1	Gene:	Adck1 / 366698	RGDID:	1308263	Length:	523	Species:	Rattus norvegicus

Alignment Length:	491	Identity:	238/491 - (48%)
Similarity:	338/491 - (68%)	Gaps:	9/491 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LASAGWSLHTNDY-DPNSLGIVRLSRSAAAVVDVALTYKRELYYKEWDKETPEYKAEKSRVHKIA 79
            ||::|..|::|.| ||:..|.||:.|:.|....::..|...|....:..|  ||...:|:||..:
  Rat    16 LAASGVYLYSNSYLDPSDFGAVRVGRAVATTAVISYDYLTSLRSVPYGSE--EYLQRRSQVHLRS 78

  Fly    80 AEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLYKVIRQDLHCNPE 144
            |.:|.:|.|.|:|.:||||||:|||:||||:|:..|:|||||.|||:.::::.:|||:||.....
  Rat    79 ARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEVRQVIREDLGKEIH 143

  Fly   145 EIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPDFK 209
            ::|.||:..|||.|||||||||.|..|..||||||||.|:..|..|:..||:.|..:.::||||:
  Rat   144 DLFLSFDDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFE 208

  Fly   210 IHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVLVMEYLEGGHVTD 274
            ..|||:|:|||||:|||||||||||||||...|.:.:|:||:|:|:.|:.|||:||::|||.|.|
  Rat   209 FMWLVDEAKKNLPLELDFLNEGRNAEKVAHMLKHFDFLKVPQIHWELSTKRVLLMEFVEGGQVND 273

  Fly   275 LDYIRRNKIDSFAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTPE-NSLEIVLLDHGLYANL 338
            ..|:.:|:||...::..:|::||||||..||||.||||||:|||:.|: ...||||||||||..|
  Rat   274 RAYMEKNRIDVNEISCHLGKMYSEMIFVNGFVHCDPHPGNVLVRKRPDTGKAEIVLLDHGLYQVL 338

  Fly   339 TDKFRYDYSNLWLSILKVDRKAMRQHSEQLGIKGDLYGLFACMVTGRPWETVMQGLTKVKYSKEE 403
            |::||.||.|||.|::..|...::.:|::|| ..|||.|||||:|.|.|.:|.||:.:...|..|
  Rat   339 TEEFRLDYCNLWQSLIWTDLDRVKYYSQRLG-AADLYPLFACMLTARSWASVKQGIGQAPVSATE 402

  Fly   404 KNTLQNNTSLVLPHISDVLEQVDRQMLLILKTNDLIRGIESTLRTQNRMTAFWVMSKCCVQSSYA 468
            .:.::||.:..||.||.:|..|.||||||||||||:|.||:||.|::..::|..||:||:: :.|
  Rat   403 DSEIRNNAACYLPEISQLLNHVPRQMLLILKTNDLLRSIETTLGTRSSASSFLNMSRCCIR-ALA 466

  Fly   469 EQRAKQSDSGS-SRILWLRVRERWELFKLNCYYLYL 503
            |.|.:  |:|| .|...:...|.:.|::::.:.|.|
  Rat   467 EHRKR--DAGSFFRRTQISFSEAFSLWQISLHELLL 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	135/251 (54%)
Adck1	XP_038968578.1	ADCK1-like	117..369	CDD:270871	136/252 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341854
Domainoid	1	1.000	227	1.000	Domainoid score	I2425
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6493
Inparanoid	1	1.050	353	1.000	Inparanoid score	I2179
OMA	1	1.010	-	-		QHG57752
OrthoDB	1	1.010	-	-		D350846at33208
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	1	1.000	-	-		oto97920
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	1	1.100	-	-	LDO	PTHR43173
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3709
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770