DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adck1 and Coq8b

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001012065.1	Gene:	Coq8b / 308453	RGDID:	1311356	Length:	528	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	96/396 - (24%)
Similarity:	178/396 - (44%)	Gaps:	50/396 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IVRLSRSAAAVVDVALTYKRELYYKEWDKETPEYKAEKSRVHKIAAEKLLQLICINKGVYIKVGQ 99
            |.||:......|.:.|....|:..|.....:.:::.....:.:..||:::|.:|..:|..:|:||
  Rat    90 ISRLASFGGLAVGLGLGALAEVTKKSLPGGSLQHEGSSPFLTEANAERIVQTLCTVRGAALKIGQ 154

  Fly   100 HIGALE-YLLPKEFVQTMKVLHSDAPQNPIEDLYKVIRQDLHCNPEEIFDSFEREPLGTASLAQV 163
            .:...: .|:..:..:..:.:...|...|...:.||:.::|..:.::...|.|..|...||:.||
  Rat   155 MLSIQDNSLISPQLQRVFERVRQSADFMPRWQMMKVLEEELGKDWQDKVASLEEVPFAAASIGQV 219

  Fly   164 HKARLKTGELVAVKVQHPYVKGNSRVDMKT----MELAVNVLARIFPDFKIHWLVEESKKNLPIE 224
            |:..||.|..||||:|:|.|..:.:.|::.    ::::|.:...:|.:..:..|.:|    |..|
  Rat   220 HQGVLKDGTEVAVKIQYPGVAESIQSDVQNLLALLKMSVGLPEGLFAEQSLQTLQQE----LAWE 280

  Fly   225 LDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVLVMEYLEGGHVTD----LDYIRRNKIDS 285
            .|:..|...|:...|......:.|||.:..:..::|||.|| |.||...|    |....||:|
  Rat   281 CDYRREAACAQTFKKLLADDPFFRVPAVVEELCTTRVLGME-LAGGIPLDQCQGLSQDIRNQI-- 342

  Fly   286 FAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTPENSLEIVLLDHGLYANLTDKFRYDYSNLW 350
               ..::.:|....:|...|:.:||:..|.|.   ..:|.::.|||.|    .:..|..::::.:
  Rat   343 ---CFQLLRLCLRELFEFRFMQTDPNWANFLY---DASSHKVTLLDFG----ASRAFGTEFTDHY 397

  Fly   351 LSILKV----DRKAMRQHSEQL----GIKGDLYG---LFACMVTGRPW-----------ETV--M 391
            :.::|.    ||..:.|.|:.|    |.:...:.   :.|.|:.|.|:           ||.  :
  Rat   398 IEVVKAAADGDRDRVLQKSQDLKFLTGFETKAFSDAHVEAVMILGEPFAASGSYDFGAGETARRI 462

  Fly   392 QGLTKV 397
            |||..|
  Rat   463 QGLIPV 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	69/266 (26%)
Coq8b	NP_001012065.1	KxGQ motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	151..154		1/2 (50%)
		ABC1_ADCK3	171..420	CDD:270872	68/265 (26%)
		AAAS motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	212..215		0/2 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810