Protein Alignment Adck1 and ADCK5

DIOPT Version :9

• Sequence 1: NP_001286851.1
• Gene: Adck1 / 37938
• FlyBaseID: FBgn0035039
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: XP_011515209.1
• Gene: ADCK5 / 203054
• HGNCID: 21738
• Length: 654
• Species: Homo sapiens
• Alignment Length: 527
• Identity: 165/527 - (31%)
• Similarity: 268/527 - (50%)
• Gaps: 65/527 - (12%)

  Fly     2 LLRRVLGYGVVGAGLASAGWSLHTNDYDPNSL-----GIVRLSRSAAAVVDVALTYKRELYYKEW 61
            |.|:||...||||.|......:.....:...:     |:.|..||....:.::|.|        |
Human   120 LWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDY--------W 176

  Fly    62 ----------DKETPEYKAEKSRVHKIAAEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTM 116
                      ::.:|.|....|..|:.||:.|:.....|.|:|:|:||.:.:..:|||.|:.:|:
Human   177 WCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTL 241

  Fly   117 KVLHSDAPQNPIEDLYKVIRQDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHP 181
            :||...|.:...:::.::..:|....|.|:|..|:.:|:..|||||||:|:|..|..||||||:.
Human   242 RVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYI 306

  Fly   182 YVKGNSRVDMKTMELAVNVLARIFPDFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSW 246
            .::.....|:.|:||.:.::..:.|.|...|::::.|..|..||||.|||||||:.|::...:.:
Human   307 DLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPY 371

  Fly   247 LRVPKIYWKYSSSRVLVMEYLEGGHVTDLDYIRRNKIDSFAVANRIGQLYSEMIFRTGFVHSDPH 311
            :.||:::|..||.|||..::..|..|.|::.||...:....:|.::.:.::|.||.|||:|||||
Human   372 VVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPH 436

  Fly   312 PGNILVRRTPENSLEIVLLDHGLYANLTDKFRYDYSNLWLSILKVDRKAMRQHSEQLGIKGDLYG 376
            |||:|||:.|:...|:||||||||..|.:|.|.....||.:|:..|..|||.|:..||::.  |.
Human   437 PGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQD--YL 499

  Fly   377 LFACMVTGRP------WETVMQGLTKVKYSKEEKNTLQNNTSLVLPHISDVLEQVDRQMLLILKT 435
            |||.|:..||      |.:.:       .|:||...:.:........:..||.::.|.|||:|:.
Human   500 LFAEMLMQRPVRLGQLWGSHL-------LSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRN 557

  Fly   436 NDLIRGIESTLRTQNRMTAFWVMSKCCVQSSYAEQRAKQSDSGSSRI------------LWLRVR 488
            .:.:|.|...|...  :..:::|:|..|:             |.||:            |....:
Human   558 INTVRAINVALGAP--VDRYFLMAKRAVR-------------GWSRLAGATYRGVYGTSLLRHAK 607

  Fly   489 ERWELFK 495
            ..||:.|
Human   608 VVWEMLK 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	98/250 (39%)
ADCK5	XP_011515209.1	AarF	202..>482	CDD:223733	107/279 (38%)
		ADCK1-like	243..483	CDD:270871	93/239 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D350846at33208
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.720