DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adck1 and AgaP_AGAP006050

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_316100.4	Gene:	AgaP_AGAP006050 / 1276722	VectorBaseID:	AGAP006050	Length:	549	Species:	Anopheles gambiae

Alignment Length:	513	Identity:	153/513 - (29%)
Similarity:	275/513 - (53%)	Gaps:	23/513 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRRVLGYGVVGAGLASAGWSLHTNDYDPNSLGIVRLSRSAAAVVDVALTYKRELYYKEWDKETPE 67
            |.|.|.||:.|:...:..:...||.:: |..|..|..||.|..:.:::.|...|  |...:....
Mosquito    32 LARSLAYGLTGSIAGAVMYDGLTNGFE-NVAGAQRFLRSFAIGLSISVDYAWSL--KGLQEGDGV 93

  Fly    68 YKAEKSRVHKIAAEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLY 132
            |:|....:|..:|:|||.....|.|:|||:||.:.|:.:::|||:|.|::.|..........::.
Mosquito    94 YEALLPEIHLRSAKKLLAGCLANGGLYIKIGQGVAAVNHIIPKEYVDTLRQLEDRCLTRQPGEVR 158

  Fly   133 KVIRQDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELA 197
            .:..||....|||:|.||:.||:..||||||.:|..::||.||||||:..::.....|::|:...
Mosquito   159 ALFVQDFGAPPEELFASFQYEPIAAASLAQVFRAVTQSGEQVAVKVQYADLRRRFDGDLRTILFL 223

  Fly   198 VNVLARIFPDFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVL 262
            ..::|.:..::...|:||:.:..|..||||::|.:|||:.|:...:..::.|||::|.:::.|:|
Mosquito   224 QRLVALLHKNYNFGWIVEDLQGTLREELDFVHEAKNAERCARDLARLDFVYVPKVFWTHTNERIL 288

  Fly   263 VMEYLEGGHVTDLDYIRRNKIDSFAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTPEN--SL 325
            ..|:::|..|:|...|...::|...:..::...:.:.||.|||||:||||||:.||:.|.|  .:
Mosquito   289 TTEFIDGCKVSDRKAIAAMQLDLAEIDRQLFTAFGQQIFSTGFVHADPHPGNVFVRKDPANPRRM 353

  Fly   326 EIVLLDHGLYANLTDKFRYDYSNLWLSILKVDRKAMRQHSEQLGIKGDLYGLFACMVTGRPWETV 390
            ::||||||||..|....|.:.:..|.:|:..|..||::.|:.|.:..  |..||.::..||.|..
Mosquito   354 QLVLLDHGLYEQLAPAVRENLARFWEAIVLRDHAAMQRFSQALNVPD--YRTFAEILLQRPLELK 416

  Fly   391 MQGLTKVKYSKEEKNTLQNNTSLVLPHISDVLEQVDRQMLLILKTNDLIRGIESTLRTQNRMTAF 455
            .:|.: .:.::::...:..........|...|..:.|.::|:::..:.||.|  .|...:.:...
Mosquito   417 GRGFS-TRLTEQDLAYMTRQAKDHFDRIMGTLRAMPRNLILVIRNLNTIRSI--ALDHGDPIDRP 478

  Fly   456 WVMSKCCVQSSYAEQRAKQSDSGSSRILWLRVRE-RWE--LFKLNCYYL----YLGLI 506
            .:|::|.:.:....:|..::      .||:..|: |:|  |::.:.:|.    ||.|:
Mosquito   479 RIMARCALAALGPARRTVRN------FLWVTFRKLRFEFLLWRQSFHYWMVSNYLKLL 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	87/252 (35%)
AgaP_AGAP006050	XP_316100.4	AarF	65..518	CDD:223733	139/465 (30%)
AgaP_AGAP006050	XP_316100.4	ADCK1-like	144..397	CDD:270871	87/252 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D350846at33208
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820