DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adck1 and adck5

DIOPT Version :9

Sequence 1:	NP_001286851.1	Gene:	Adck1 / 37938	FlyBaseID:	FBgn0035039	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001189455.1	Gene:	adck5 / 100001584	ZFINID:	ZDB-GENE-081104-149	Length:	579	Species:	Danio rerio

Alignment Length:	487	Identity:	163/487 - (33%)
Similarity:	274/487 - (56%)	Gaps:	34/487 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GIVRLSRSAAAVVDVALTY--KRELYYKEWDKETPEYKAEKSRVHKIAAEKLLQLICINKGVYIK 96
            ||.|..||....:.::..|  ...:..:..|:.:||:..:.|..|:.||..::.....|.|:|||
Zfish    83 GIGRFCRSLYVGLMISADYWWTSNIALRGMDESSPEFLKQMSACHQRAASNMVDGAIQNGGLYIK 147

  Fly    97 VGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLYKVIRQDLHCNPEEIFDSFEREPLGTASLA 161
            :||.:.|..:|||.|::||:.||...|.....:::..:.::|.:..|:::|.:|:.||:..||||
Zfish   148 LGQGLCAFNHLLPPEYIQTLHVLEDKALNRRYKEVDALFQEDFNMTPDKMFRTFDYEPVAAASLA 212

  Fly   162 QVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPDFKIHWLVEESKKNLPIELD 226
            |||||.|..|..||||||:..::.....|::|:|:.::|:..:.|.|...|::::.|..|..|||
Zfish   213 QVHKAELHDGTPVAVKVQYIDLRDRFDGDIRTLEILLDVIKFMHPSFGFRWVLQDLKGTLAQELD 277

  Fly   227 FLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVLVMEYLEGGHVTDLDYIRRNKIDSFAVANR 291
            |.|||||:|:.|::.|.:.::.|||::|..:|.|||..||.:|..:.:::.|:|..:.....|::
Zfish   278 FENEGRNSERCAEELKHFKFVVVPKVFWDVTSKRVLTAEYCDGCKINNVEEIQRQGLSLKDTADK 342

  Fly   292 IGQLYSEMIFRTGFVHSDPHPGNILVRRTPENSLEIVLLDHGLYANLTDKFRYDYSNLWLSILKV 356
            :.::::|.||.|||:|:||||||:||||.|:...|:||||||||.:|:...|.....||.:|:..
Zfish   343 LIRIFAEQIFYTGFIHADPHPGNVLVRRGPDKKAELVLLDHGLYEHLSKSDRAALCQLWRAIILR 407

  Fly   357 DRKAMRQHSEQLGIKGDLYGLFACMVTGRP---WETVMQGLTKVKYSKEEKNTLQNNTSLVLPHI 418
            |...|:.::.|||:|.  |.||:.|:..||   |:.   ||..: .:.||.:.:::........|
Zfish   408 DDAGMKTYANQLGVKE--YFLFSEMLLQRPINMWDL---GLGNI-LTGEETSYMRDMAINRFDKI 466

  Fly   419 SDVLEQVDRQMLLILKTNDLIRGIESTLRTQNRMTAFWVMSKCCVQSSYAEQRAKQSDSGSSRIL 483
            ..||:.:.|.|||:.:..:.:|.|..||...  :..:::|:||.|:   ...||:..|
Zfish   467 MQVLKSMPRPMLLVFRNINTVRCINITLGAP--VDRYFIMAKCAVR---GHGRAQAED------- 519

  Fly   484 WLRVRERWELFKLNCYYLYLGLINFGFLEALK 515
             :|:..|..:|:..|          .|.|:||
Zfish   520 -IRLFSRLSVFRWVC----------SFWESLK 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adck1	NP_001286851.1	ADCK1-like	118..369	CDD:270871	96/250 (38%)
adck5	NP_001189455.1	AarF	78..499	CDD:223733	148/423 (35%)
adck5	NP_001189455.1	ADCK1-like	169..420	CDD:270871	96/250 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D350846at33208
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720