Protein Alignment CG4707 and Pogz

DIOPT Version :10

• Sequence 1: NP_611944.1
• Gene: CG4707 / 37935
• FlyBaseID: FBgn0035036
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_008759517.1
• Gene: Pogz / 310658
• RGDID: 1309980
• Length: 1410
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 124/670 - (18%)
• Similarity: 211/670 - (31%)
• Gaps: 174/670 - (25%)

  Fly    82 PIEFCGQTEEAIINPLYSVELDALAEAF---------FAPSEVKVEVN----------ELEPLPK 127
            |::..........:|:.|..:....:.|         .|.::|.:.:|          .|.|.|.
  Rat   128 PVQVMQNANHVTSSPVASQPIFITTQGFPVRNVRPVQNAMNQVGIVLNVQQGQTVRPITLVPAPG 192

  Fly   128 VELLEDPVKTEIRTAPKRLGVPNEGSPHSKRRIKNELPVDSDSDAPLADFLNSDSKRSSVGPAKN 192
            .:.::..|           |||...|..:..|..:.:||...::........:.:.||:| |...
  Rat   193 TQFVKPTV-----------GVPQVFSQMTPVRPGSTMPVRPTTNTFTTVIPATLTIRSTV-PQSQ 245

  Fly   193 SEANKGRQLRRSARRGRPPKAKPESAPSPKKELDSEDGEENARDNNDM--EFVAPEAVLGTDDSS 255
            |:..|......:......|.|..:.|..|       .|:.|...|..:  .|.:|.||......:
  Rat   246 SQQTKSTPSTSTTPIATQPTALGQLAGQP-------PGQPNQTSNPKLAPSFPSPPAVSIASFVT 303

  Fly   256 SSSSESSGEDSD---------HSLPDIEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRLSREEI 311
            ......:||:|:         :::|.:      .:.|..|||..
  Rat   304 VKRPGVTGENSNEVAKLVNTLNTIPSL------GQSPGPVVVSN--------------------- 341

  Fly   312 ERRKLQQDEYDEIILQFFKKFPCSLCNLLVQNFADMRRHQRVSHNI------ESGYIEC--CGRK 368
                                      |...|..:......:|:.:|      :.|...|  |..:
  Rat   342 --------------------------NSSAQRTSGPESSMKVTSSIPVFDLQDGGRKICPRCNAQ 380

  Fly   369 FHLRKALAEHVLVHKNPDHFMCSQCGRVFQ---DSRALEVHEQTHT-----NPEVKA-------- 417
            |.:.:||..|          ||..|..:.:   ..::|:......:     :||..|
  Rat   381 FRVTEALRGH----------MCYCCPEMVEYQKKGKSLDAEPSVPSAAKPASPEKTAPVTSTPSS 435

  Fly   418 ------EPKEKRIYQCEKCPKSFTTKAAMEYHDV-----------SKHVPKSEFKYSCPECNKKI 465
                  .|..|.....|....:..||..|...|.           ....||....:.||.|.|::
  Rat   436 TPIPALSPPTKVPEPSESAGDTVQTKLIMLVDDFYYGRDGGKAAQLTSFPKVATSFRCPHCTKRL 500

  Fly   466 PTERKLKEHLRYMH--------DPEAAIICDKCGKTLRSQTNLKKHHELEHSEKPRPKPDPVQCE 522
            ....:...|::: |        :.:...||..|.:...:...|:.|.|..||    |.....:|:
  Rat   501 KNNIRFMNHMKH-HVELDQQNGEVDGHTICQHCYRQFSTPFQLQCHLENVHS----PYESTTKCK 560

  Fly   523 ICGTWLRHLSGL-KQHMKTVHEPPGDEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCEKA 586
            || .|......| .||||..|:|....:.|.:|...|:....:..|....|...|...|..|.|.
  Rat   561 IC-EWAFESEPLFLQHMKDTHKPGEMPYVCQVCQYRSSLYSEVDVHFRMIHEDTRHLLCPYCLKV 624

  Fly   587 FKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPN---IMKI 648
            ||.....::|...|....:|.|..|.:.|....:..:|:.:.|:...:..:.:.|.|.   .::.
  Rat   625 FKNGNAFQQHYMRHQKRNVYHCNKCRLQFLFAKDKIEHKLQHHKTFRKPKQLEGLKPGTKVTIRA 689

  Fly   649 SQG--ATTAMKKRQT-SGAL 665
            |:|  .|..:..... ||||
  Rat   690 SRGQPRTVPVSSNDAPSGAL 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4707	NP_611944.1	zf-AD	3..77	CDD:462262
		C2H2 Zn finger	334..355	CDD:275368	3/20 (15%)
		LIM	<361..407	CDD:413332	10/50 (20%)
		C2H2 Zn finger	365..382	CDD:275368	5/16 (31%)
		C2H2 Zn finger	390..410	CDD:275368	3/22 (14%)
		C2H2 Zn finger	427..443	CDD:275368	4/15 (27%)
		COG5236	<455..>574	CDD:227561	31/127 (24%)
		C2H2 Zn finger	458..476	CDD:275368	5/17 (29%)
		C2H2 Zn finger	487..507	CDD:275368	5/19 (26%)
		C2H2 Zn finger	521..540	CDD:275368	8/19 (42%)
		C2H2 Zn finger	551..572	CDD:275368	4/20 (20%)
		C2H2 Zn finger	580..600	CDD:275368	6/19 (32%)
		C2H2 Zn finger	608..629	CDD:275368	4/20 (20%)
Pogz	XP_008759517.1	PHA03247	264..>458	CDD:223021	40/263 (15%)
		C2H2 Zn finger	493..526	CDD:275371	6/33 (18%)
		C2H2 Zn finger	529..550	CDD:275368	5/20 (25%)
		C2H2 Zn finger	559..580	CDD:275368	9/21 (43%)
		C2H2 Zn finger	589..610	CDD:275368	4/20 (20%)
		C2H2 Zn finger	618..638	CDD:275368	6/19 (32%)
		CENPB	1018..1079	CDD:197828
		DDE_3	1159..>1270	CDD:481203