DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4707 and LOC1276170

DIOPT Version :10

Sequence 1:NP_611944.1 Gene:CG4707 / 37935 FlyBaseID:FBgn0035036 Length:673 Species:Drosophila melanogaster
Sequence 2:XP_315481.4 Gene:LOC1276170 / 1276170 VectorBaseID:AGAMI1_000612 Length:526 Species:Anopheles gambiae


Alignment Length:647 Identity:158/647 - (24%)
Similarity:249/647 - (38%) Gaps:188/647 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 CVLCLDSSNAGYGLQSEEGVRLNIR-----ATIHKHFAFSEVLTAGGDAEVCRECWNCVSSFEEF 63
            |.|||       |..|..|.:::||     ..:...|.|..:|.......||.||.:.||....:
Mosquito    46 CRLCL-------GSLSSTGPKISIRDAEFQEELKTVFHFDIILDTALPEHVCNECRSTVSYCHSY 103

  Fly    64 HQRVSCLHRQRSSDSKSEPIEFCGQTEEAIINPLYSVELDALAEAFFAPSEVKVEVNELEPLPKV 128
                 ||..|      :...:..|:..|.::.|:.:|.:::|.|.                    
Mosquito   104 -----CLQVQ------ANQFQLLGEANENVLKPVENVMVESLVEE-------------------- 137

  Fly   129 ELLEDPVKTEIRTAPKRLGVPNEGSPHSKRRIKNELPVDSDSDAPLADFLNSDSKRSSVGPAKNS 193
               :|..|||                  |...|.||.|:.::...|.|       |..:...::.
Mosquito   138 ---DDCTKTE------------------KHLQKEELAVNQEATMCLED-------REGLSVDEDC 174

  Fly   194 EANKGRQLRRSARRGRPPKAKPESAPSPKKELDSEDGEENARDNNDMEFVAPEAVLGTDDSSSSS 258
            ...|..:.||.||:....|      |..:||.:::|                          :||
Mosquito   175 VRGKNDKQRRRARQSIKNK------PDLQKETENQD--------------------------TSS 207

  Fly   259 SESSGEDSDHSLPDIEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRLSREEIERRKLQQDEYDE 323
            .|.|                                                    :..|.|.|:
Mosquito   208 KEVS----------------------------------------------------QANQLENDK 220

  Fly   324 IILQFFKKFPCSLCNLLVQNFADMRRHQRVSHNIESGYIECCGRKFHLRKALAEHVLVHKNPDHF 388
            ||.||| ...|.:|....::|..:..|.|.:|..: ||:.|||::|..|..|.:|:..|:..  .
Mosquito   221 IITQFF-TLECEICAATAESFVQLLDHYRTAHKTK-GYVRCCGKQFFRRYILVDHIAAHRGT--I 281

  Fly   389 MCSQCGRVFQDSRALEVH-EQTHTNPEVKAEPKEKRIYQCEKCPKSFTTKAAMEYHDVSKHVPKS 452
            .|..|.:.::..|.|.:| .::|:.       :..|.::|.||..|:..:..:..|:: .||   
Mosquito   282 RCEICHKTYKTKRYLALHFAKSHSG-------ETDRPFKCGKCHVSYPKQYLLRAHEL-MHV--- 335

  Fly   453 EFKYSCPECNKKIPTERKLKEHLRYMHDPEAAIICDKCGKTLRSQTNLKKHHELEHS-----EKP 512
              :..|..|.|.:...:.|:.|:..||..:...|||.|||..|::..:::|.. ||.     |: 
Mosquito   336 --QQQCHICEKVLSNTQSLRVHIAQMHGGDGHHICDTCGKVFRTKPAMERHIN-EHMGVDVVER- 396

  Fly   513 RPKPDPVQCEICGTWLRHLSGLKQHMKTVHEPPGDEHRCHICNKTSTNSRALKRHIYHNHLCERK 577
                  :||:.|..|......|::|::.:|...|...||.:|...|.|||||..|....|: |.:
Mosquito   397 ------LQCDHCQKWFSGKYNLRKHVRFMHLEGGQVFRCELCPHESPNSRALANHKLRVHV-EER 454

  Fly   578 FKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCP-MTFFSNANMYKHRQRLHRAEWEADRK 638
            |:|..|.|.|||..:||||.::||...||:|..|. .||.|.||.:.||:..|..||||.::
Mosquito   455 FECEYCGKRFKRRPNLREHIASHTNMPLYSCEICQNRTFNSKANYFTHRKHKHPQEWEAQKR 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4707NP_611944.1 zf-AD 3..77 CDD:462262 21/77 (27%)
C2H2 Zn finger 334..355 CDD:275368 5/20 (25%)
LIM <361..407 CDD:413332 14/46 (30%)
C2H2 Zn finger 365..382 CDD:275368 6/16 (38%)
C2H2 Zn finger 390..410 CDD:275368 5/20 (25%)
C2H2 Zn finger 427..443 CDD:275368 4/15 (27%)
COG5236 <455..>574 CDD:227561 37/123 (30%)
C2H2 Zn finger 458..476 CDD:275368 5/17 (29%)
C2H2 Zn finger 487..507 CDD:275368 7/19 (37%)
C2H2 Zn finger 521..540 CDD:275368 5/18 (28%)
C2H2 Zn finger 551..572 CDD:275368 9/20 (45%)
C2H2 Zn finger 580..600 CDD:275368 10/19 (53%)
C2H2 Zn finger 608..629 CDD:275368 9/21 (43%)
LOC1276170XP_315481.4 None

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