DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4707 and LOC1274221

DIOPT Version :10

Sequence 1:NP_611944.1 Gene:CG4707 / 37935 FlyBaseID:FBgn0035036 Length:673 Species:Drosophila melanogaster
Sequence 2:XP_562406.5 Gene:LOC1274221 / 1274221 VectorBaseID:AGAMI1_012130 Length:768 Species:Anopheles gambiae


Alignment Length:811 Identity:206/811 - (25%)
Similarity:320/811 - (39%) Gaps:205/811 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 CVLCLDSSNAGY-GLQSEEGVRLNIRATIHKHFAFSEVLTAGGDAEVCRECWNCVSSFEEFHQRV 67
            |||||.:....: .:.:||....:|.:.|.||.    .:....|:.||.|||.|::.|.||:.::
Mosquito     7 CVLCLTTEPQSFLKVYNEEKQDTDIASVITKHL----WVKPAKDSYVCDECWKCLNDFHEFYTKL 67

  Fly    68 SCLHRQ--------RSSDSKSEPIEFCGQTEEAIINPLYSVELDALAEAFFAPSEVKVEVNELEP 124
            ..:|..        .:.|.:....||         :|:..|:::.|::.  |....::|...||.
Mosquito    68 ENIHYPPDPEDASCNAKDIRQYLFEF---------HPVEDVKIEELSQN--AEDMEEIEYEYLEA 121

  Fly   125 LPKVELLEDPVKTEIRTAPKRLGVPNEGS-PHSKRRIK-------------NELPVDSDSD---- 171
            ..     |:.::.|  .|.:..|.|...| ..:..:|:             ||...|.|.|    
Mosquito   122 CN-----EETIENE--NAERSSGRPKRASAAQANYKIEAAESEWEKDYLATNEDEYDDDDDDDDE 179

  Fly   172 ---------APLADFLNSDSKRSSV----GPAKNSEANKGRQLRRSAR--------RGRPPKAKP 215
                     ....|:|..|:..|.|    .|:| ::...|.:...::.        |||||||||
Mosquito   180 ADADYNGDEKEEVDYLEEDNDDSEVINYDSPSK-AKQEPGTKKEPASEPTSPPKRGRGRPPKAKP 243

  Fly   216 --ESAPSPKKEL--------------DSE---------DGEENARDNNDM--------------- 240
              |..|.||.:|              |||         |||:..:..|..               
Mosquito   244 EIEIKPEPKSKLRRRGRKRKVSVSSSDSELESDFDDFIDGEDWKKYRNTSKDKGRRSLGFRQLQE 308

  Fly   241 -------EFV---APEAVLGTD--------------------DSSSSSSESSGEDSDHSLPDIEP 275
                   ||:   .||.::...                    ........:.|....|.....:|
Mosquito   309 KIFSYVDEFICYYCPEKIVFERFHHANLHYKKVHNEPAFLRCPKCGKKCFTPGGFVSHMETHEDP 373

  Fly   276 EERYAEIPKRVV---VKPKKYRKR-----EKPLVPPVRL---------SREEIER---RKL---Q 317
            |....:|..:|.   :..||:.:.     ||....|..|         .||:.||   ||:   :
Mosquito   374 ERNKCKICGKVTDQEITLKKHMRAHQENLEKDFPYPCSLCNRRFEEEEKREKHERLHGRKVIIKK 438

  Fly   318 QDEYDEIILQFFKKFPCSLC------NLLVQNFADMRRHQRVSHNIESGYIEC--CGRKFHLRKA 374
            :...|..:|:|:|:..|.:|      :....||.|::.|....|| ::.:::|  |.:|...|:.
Mosquito   439 EKGRDLELLEFYKRIYCEVCEEKKPESTSFDNFWDLKVHMGNEHN-KTPFLKCPICFKKNVCRQQ 502

  Fly   375 LAEHVLVHKNPDHFMCSQCGRVFQDSRALEVHE-QTHTNPEVKAEPKEKRIYQCEKCPKSFTTKA 438
            |..||.||.||:::.|..|..:.|:   ||.|. :.|| ||... |.||. |.||.|.|.|..:.
Mosquito   503 LMVHVDVHNNPENYRCEVCKEIHQN---LEKHMIKAHT-PETSL-PDEKN-YSCEHCGKMFKYQT 561

  Fly   439 AMEYHDVSKHVPKSEFKYSCPECNKKIPTERKLKEHLRYMHDPEAAIICDKCGKTLRSQTNLKKH 503
            .::.|....|..|.   .||..|:|.. ..:.|..|.|..|..| ..:|:.|.|..::::.|:. 
Mosquito   562 NLKSHIDRVHGVKD---VSCDICHKYF-NSKALSAHKRSAHTDE-MFMCEHCPKMFKTRSGLES- 620

  Fly   504 HELEHSEKPRPKPDPVQCEICGTWLRHLSGLKQHMKTVHEPPGDEHRCHICNKTSTNSRALKRHI 568
            |:.:|.|..|..   |||.|||..:|..:.:.:||||:|... |...|.:|.|....:..:.|| 
Mosquito   621 HKSDHDETLRKS---VQCLICGKEMRRGASMAKHMKTIHSQE-DPVSCDLCGKVFRTTFHMMRH- 680

  Fly   569 YHNHLC-----ERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRL 628
             ..:.|     .|.:||.:|.|.|.....:.||.:|||...||.|..|..||...:|:||||::.
Mosquito   681 -RANTCSATIDSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKA 744

  Fly   629 HRAEWEADRKKPLPPNIMKISQGATTAMKKR 659
            |..||:..:.:|        .||..|.::.|
Mosquito   745 HPLEWQEVQARP--------EQGIATVIEIR 767

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4707NP_611944.1 zf-AD 3..77 CDD:462262 22/81 (27%)
C2H2 Zn finger 334..355 CDD:275368 6/26 (23%)
LIM <361..407 CDD:413332 16/47 (34%)
C2H2 Zn finger 365..382 CDD:275368 6/16 (38%)
C2H2 Zn finger 390..410 CDD:275368 6/20 (30%)
C2H2 Zn finger 427..443 CDD:275368 5/15 (33%)
COG5236 <455..>574 CDD:227561 35/118 (30%)
C2H2 Zn finger 458..476 CDD:275368 5/17 (29%)
C2H2 Zn finger 487..507 CDD:275368 5/19 (26%)
C2H2 Zn finger 521..540 CDD:275368 7/18 (39%)
C2H2 Zn finger 551..572 CDD:275368 5/20 (25%)
C2H2 Zn finger 580..600 CDD:275368 6/19 (32%)
C2H2 Zn finger 608..629 CDD:275368 9/20 (45%)
LOC1274221XP_562406.5 None

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